联合检测Hcy hs－CRP在冠心病合并急性脑梗死患者中的预测作用研究

目的：：探讨Hcy、hs－CRP 联合检测在冠心病和急性脑梗死患者中的预测价值；方法：选择冠心病患者共142例为研究对象，其中合并急性脑梗死的患者共31例(冠心病＋脑梗死组)，不合并者共111例(冠心病组)。另纳入65例脑梗死患者(脑梗死组)和93例健康体检者(健康对照组)，探讨各组血清Hcy、hs－CRP 水平的变化及其预测价值。结果：冠心病＋脑梗死组患者血清Hcy和hs－CRP 水平显著高于冠心病组、脑梗死组和健康对照组。两组联合检测所测得阳性率均能明显提高，显著高于单独Hcy检测。其中两者联合检测在冠心病＋脑梗死组检测的阳性率最高，高于冠心病组和脑梗死组。结论：联合检测Hcy、hs－CRP 在冠心病合并急性脑梗死患者中的预测价值，值得临床应用。

Study on the Predictive Effect of Combined Detection of Hcy and hs-CRP in Coronary Heart Disease Patient with Acute Cerebral Infarction

Objective:To study the predictive effect of combined detection of Hcy and hs-CRP in coro-nary heart disease ( CHD) patient with ( ACI) . Methods: A total 142 cases of CHD patients were collected for the study, in which 31 patients with acute cerebral infarction ( coronary heart disease and cerebral infarc-tion group) and a total of 111 cases were not consolidated ( CHD group) . 65 cases of cerebral infarction ( cer-ebral infarction group ) was also included and 93 healthy subjects ( healthy controls ) was collected for the study. The serum levels of Hcy and hs-CRP and its change in predictive value were explored. Results:Serum levels of Hcy and hs-CRP in patients with coronary heart disease and cerebral infarction were significantly higher than the CHD group, cerebral infarction group and the healthy control group. Positive rates in two com-bined detection groups increased significantly, which was significantly higher than detection alone. The com-bined detection in coronary heart disease and cerebral infarction group had the highest positive rate, which was higher than CHD and cerebral infarction group. Conclusion:Combined detection of Hcy, hs-CRP in patients with acute cerebral infarction merged the coronary heart disease had a predictive value, which is worthy of clinical application.