腹腔镜卵巢打孔治疗难治性多囊卵巢综合征不孕患者26例临床分析

目的:探讨腹腔镜手术治疗难治性多囊卵巢综合征(PCOS)不孕患者的治疗效果。方法:2004年3月至2007年3月对我院26例难治性PCOS患者行腹腔镜下卵巢打孔术及输卵管通液术。手术前后分别测血清黄体生成素(LH)卵泡刺激素(FSH),雄激素(T)水平、术后监测排卵情况,妊娠率及妊娠结果。结果:术后的LH及T水平较术前有显著下降,FSH及PRL水平无明显变化,术后有20例患者发生排卵,14例成功妊娠,3例即使在加用cc后仍无排卵与妊娠。结论:腹腔镜卵巢打孔术能明显改善难治性PCOS患者的排卵和受孕机会,不失为难治性PCOS不孕患者的一种有效治疗手段。

Clinical Study on the Treatment of Clomiphene-resistant Polycystic Ovarian Syndrome with Laparoscopic Ovarian Drilling on 26 Patients

Objective:To evaluate the efficacy of laparoscopic ovarian drilling in treating clomiphene-resistant polycystic ovary syndrome(PCOS).Method:From March 2004 to March 2007,26 cases diagnosed as PCOS received laparoscopic ovarian drilling.Measure the serum concentrations of LH,FSH,and the androgen(T) before and after the operation,Ovarian follicular development,pregnancy rate and abortion rate were observed after the operation.Results:There were significant declining of LH and T after the operation.FSH and PRL changed little after the operation.The ovulation number is 20,the pregnancy number is 14 after the operation,3 cases can't ovulate and be pregnant though they were cured by clomiphene.Conclusion:Laparoscopic ovarian drilling can significantly increase the ovulation rate and pregnancy rate on patients with CC-resistant PCOS.