首页 | 本学科首页   官方微博 | 高级检索  
检索        

212例急性乳腺炎患者乳腺脓液细菌培养及药敏分析
引用本文:张镇松,刘秀卿.212例急性乳腺炎患者乳腺脓液细菌培养及药敏分析[J].河北医学,2009,15(7):821-823.
作者姓名:张镇松  刘秀卿
作者单位:广东省汕头市妇女儿童医院检验科,广东汕头,515041
摘    要:目的:了解急性乳腺炎患者乳腺脓液标本中病原菌的分布及药物敏感性情况,为临床合理使用抗生素提供指导。方法:收集从乳腺炎患者乳腺脓肿中抽出的脓液标本经需氧培养分离后,再鉴定到种并用K-B法进行相应的药敏试验。结果:212份脓液标本分离出104株病原菌,分离率为49.1%,其中金黄色葡萄球菌93株,占89.4%;表皮葡萄球菌10株,占9.6%.草绿色链球菌1株,占1.0%。葡萄球菌对青霉素的耐药率为98.9%,对苯唑西林的敏感率为84.5%。对万古霉素的敏感率为100%,对环丙沙星、氧氟沙星、丁胺卡那的耐药率分别为18.4%、17.5%、14.6%,对头孢拉定(头孢一代)、西力欣(头孢二代)、头孢曲松(头孢三代)、头孢吡肟(头孢三代)的耐药率分别为33.0%、13.5%、11.7%、6.8%。对红霉素的耐药率高达80%以上,对复方新诺明和阿奇霉素的耐药率也在50%以上。结论:急性乳腺炎患者感染的主要病原菌为金黄色葡萄球菌,对青霉素、红霉素的耐药率较高,两者均不能作为治疗乳腺炎的首选药,而对耐青霉素酶的苯唑西林敏感率较高而且考虑乳腺炎患者大多处于哺乳期的用药安全,因此可用苯唑西林作为治疗大部分葡萄球菌引起的乳腺炎的首选药,但因为耐甲氧西林金黄色葡萄球菌(MRSA)的出现,且耐甲氧西林金黄色葡萄球菌(MRSA)的感染具有明显多重耐药性,所以临床医生必须重视治疗前标本的采集培养,根据药敏结果选用合理的抗生素。

关 键 词:乳腺炎  金黄色葡萄球菌  细菌耐药性

The Germiculture and Drug Sensitive Test of the Liquor Puris from 212 Acute Mastitis Patients
ZHANG Zhen-song,LIU Xiu-qing.The Germiculture and Drug Sensitive Test of the Liquor Puris from 212 Acute Mastitis Patients[J].Hebei Medicine,2009,15(7):821-823.
Authors:ZHANG Zhen-song  LIU Xiu-qing
Institution:ZHANG Zhen - song, LIU Xiu - qing ( The Women and Children's Hospital of Shantou, Guangdong Shantou 515041, China )
Abstract:Objective: To explore the distribution and drug sensitivity instance of pathogenic bacteria in the liquor puffs from acute mastitis patients, providing basis for the application of antibiotic clinically. Method: The samples was aerobic cultured and genus identified. Secondaly, the drug sensitive tests were made with K- B method. Result: 104 positive were detected from all 212 samples, the collected rate was 49. 1%. 93 staphylococcus aureus samples were detected (89.4% );10 Staphylococcus epidermidis samples were detected( 9.6% staphylococci to penic ; 1 streptococcus viridans sample was detected( 1% ) . The drug tolerance rate of llin was 98.9%, 84.5% to oxacillin, 100% to vancomycin, 33.0% to cefradine, 13. 5% to Cefuroxime,ll. 7% to cefatriaxone,6.8% to cefepime, above 80% to erythromycin, above 50% to cotrimoxazole or Azithromycin. Conclusion : The most common pathogenic bacteria of acute mastitis patients is staphylococcus aureus, its drug tolerance rate to penicillin and erythromycin is so high that both penicillin and erythromycin are not the first choice for mastitis patients. Oxacillin can be the first choice for most mastitis patients . With the emergence of MRSA, doctors should think much of the collection and culture of samples before treatment, and use antibiotic based on the drug tolerance test.
Keywords:Mastitis  Staphylococcus aureus  Bacterial drug resistance
本文献已被 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号