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热敏灸对抑郁症模型大鼠行为学的影响
引用本文:肖爱娇,康明非,陈日新,肖东北,曹丹.热敏灸对抑郁症模型大鼠行为学的影响[J].江西中医学院学报,2011,23(4):24-28.
作者姓名:肖爱娇  康明非  陈日新  肖东北  曹丹
作者单位:1. 江西中医学院生理学教研室 南昌330004
2. 江西中医学院附属医院针灸康复科 南昌330006
3. 江西中医学院2007级生物工程班 南昌330006
基金项目:江西省教育厅科技项目,江西省卫生厅中医药科研项目,江西中医学院科研课题
摘    要:目的:制备抑郁症大鼠模型,观察热敏灸"百会"对抑郁症大鼠模型行为学结果的影响,了解热敏灸"百会"治疗抑郁症的效果。方法:用雌性SD大鼠,采用孤养和慢性不可预见性温和应激(CUMS)制备抑郁症大鼠模型。以Open-Field测试大鼠的直立活动和水平活动得分;以1h内大鼠摄入饮用水和蔗糖水量计算糖水消耗百分比;以Morris水迷宫测试大鼠的学习记忆力。结果:与模型组相比,热敏灸组大鼠的水平活动得分和直立活动得分均增加;糖水消耗百分比升高;逃避潜伏期缩短。结论:热敏灸"百会"具有改善抑郁症的效果。

关 键 词:热敏灸  抑郁症  慢性不可预见性温和应激

Effect of Heat-sensitive Moxibustion on Behavioral Results in Depression Model Rats
XIAO Ai-jiao,KANG Ming-fei,CHEN Ri-xin,XIAO Dong-bei,CAO Dan.Effect of Heat-sensitive Moxibustion on Behavioral Results in Depression Model Rats[J].Journal of Jiangxi College of Traditional Chinese Medicine,2011,23(4):24-28.
Authors:XIAO Ai-jiao  KANG Ming-fei  CHEN Ri-xin  XIAO Dong-bei  CAO Dan
Institution:XIAO Ai-jiao1,KANG Ming-fei2,CHEN Ri-xin2,XIAO Dong-bei3,CAO Dan3 1.Department of Physiology,Jiangxi University of Traditional Chinese Medicine.Nanchang,330004,2.The Afflliated Hospital of Traditional Chinese Medicine,Nanchang 330006,3.Jiangxi University of Traditional Chinese Medicine
Abstract:Objective: To observe the effect of heat-sensitive moxibustion on behavioral results in depression model rats.Methods: Female SD rats are induced into depression model by giving alone in combination with 21 days of chronic unexpected mild stress.Open-Field was used to test crossing and rearing,Sucrose consumption test was used to calculate the percentage of sucrose intake,Morris water maze was employed to evaluate learning and memory abilities.Results: Compared to rats in the model group,rats in the heat-se...
Keywords:Heat-sensitive Moxibustion  Depression  Chronic Unexpected Mild Stress  
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