Alterations in lymphocyte subset patterns and co-stimulatory molecules in patients with Alzheimer disease |
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作者单位: | Department of Neurology, First Affiliated Hospital of SooChow University, Suzhou, Jiangsu 215006, China |
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基金项目: | SooChow University “211 Project” of Jiangsu Provincial Government,No. R2317176; |
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摘 要: | Alzheimer disease (AD) is characterized by the .presence of β-amyloid (Aβ) plaques in the brain.More evidence of inflammatory parameters, such as, complement factors, proinflammatory cytokines and lymphocytes has been found to be co-localized with Aβ plaques. The research in the past decades has demonstrated abnormalities of both the humoral and cellular immune responses, suggesting an association of immunological aberration and AD. The total percentage of lymphocytes was not found to be altered,
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关 键 词: | 阿尔茨海默病患者 淋巴细胞亚群 共刺激分子 改建 炎性细胞因子 细胞免疫反应 淀粉样蛋白 免疫学异常 |
Alterations in lymphocyte subset patterns and co-stimulatory molecules in patients with Alzheimer disease |
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Authors: | XUE Shou-ru XU Dong-hua YANG Xin-xin DONG Wan-li |
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Institution: | Department of Neurology, First Affiliated Hospital of SooChow University, Suzhou, Jiangsu 215006, China |
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Abstract: | lymphocytes costimulatory molecule Alzheimer disease |
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Keywords: | lymphocytes costimulatory molecule Alzheimer disease |
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