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EFFECTS OF ELECTROLYTIC LESIEONS OR INTRACEREBRAL INJECTIONS OF 5,6-DIHYDROXYTRYPTAMINE IN RAPHE NUCLEI ON ACUPUNCTXJRE ANALGESIA IN RATS
Authors:C Chen-yu  T Huan-chi  C Yen-fang  P Yao-hui  K Hsi-ken  C Jui-kang  S Hong-ying  Y Fu-yao
Abstract:Experiments on restrained rats showed that the pain responses thrcsholds {tail-flick and vocalization) induced by rioxious, stimuli were increased markedly after clectroacupuncturc. Following electrolytic lcsions or specific 5-HT neuronal intoxication by 5,6-dihydroxytrypta- mine in nucleus raphe magnus, dorsalis or me- dianus, the acupuncture effects wcre significantly reduced on the early postoperative days. It is inferred that the rauhe serotonergic system may play an important role in the analgesic cffect of acupuncture. A neural mechanisrrt iii acupunc- ture analgesia is hypothesized
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