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Efficacy of acupuncture and moxibustion in treating Bell’s palsy: a multicenter randomized controlled trial in China
作者姓名:Li Y  Liang FR  Yu SG  Li CD  Hu LX  Zhou D  Yuan XL  Li Y  Xia XH
作者单位:[2]AcupunctureandTuinaCollege,ChengduUniversityofTCM,Chengdu610075,China [3]FirstAffiliatedHospitalofChengduUniversityofTCM,Chengdu610075,China [4]WestChinaHospital,SichuanUniversity,Chengdu610042,China [5]TCMHospitalofMianyangCity,Mianyang621000,China [6]People'sHospitalofSichuanProvince,Chengdu610075,China
基金项目:ThisstudywassupportedbytheClinicalFoundationoftheStateAdministrationofTCM (No 0 0 0 1LP5 0 )
摘    要:Background Bell‘s palsy involves acute facial paralysis due to inflammation of the facial nerve. Acupuncture and moxibustion (acu-moxi) is beneficial in treating facial palsy. In order to verify the efficacy of acu-moxi on Bell‘s palsy, a randomized single-blind, multicenter clinical trial was performed.Methods A total of 480 patients from four clinical centers were involved in this trial, of whom 439 completed the trial and 41 did not. All patients were randomly assigned to either the control group or to one of two treatment groups. The control group was treated with prednisone, vitamin B1, vitamin B12,and dibazole; the treatment groups were treated either with acu-moxi alone or in combination with prednisone, Vitamin B1, vitamin B12, and dibazole. Symptoms and signs, the House-Brackmann scale, and facial disability index (FDI) scores were assessed and determined both pre- and post-treatment to evaluate the effectiveness of the treatment methods. Results The characteristics of the control and two treatment groups were comparable without statistically significant differences before treatment. There were significant differences between the control and treatment groups after treatment (X^2=15.265, P=0.018). According to evaluations based on the House-Brackmann scale and FDI scores, the effectiveness of treatment in the two treatment groups was better than in the control group and was most effective in patients receiving acumoxi treatment alone (Z=-2.827, P=0. 005).Conclusion The efficacy of acu-moxi treatment for Bell‘s palsy is verified scientifically.

关 键 词:针刺疗法  艾灸  Bell's瘫痪  多通道  随机控制试验  中医

Efficacy of acupuncture and moxibustion in treating Bell's palsy: a multicenter randomized controlled trial in China
Li Y,Liang FR,Yu SG,Li CD,Hu LX,Zhou D,Yuan XL,Li Y,Xia XH.Efficacy of acupuncture and moxibustion in treating Bell's palsy: a multicenter randomized controlled trial in China[J].Chinese Medical Journal,2004,117(10):1502-1506.
Authors:Li Ying  Liang Fan-rong  Yu Shu-guang  Li Chang-du  Hu Ling-xiang  Zhou Dong  Yuan Xiu-li  Li Yi  Xia Xiao-hong
Institution:1. Acupuncture and Tuina College,Chengdu University of TCM,Chengdu 610075,China
2. First Affiliated Hospital of Chengdu University of TCM,Chengdu 610075,China
3. West China Hospital,Sichuan University,Chengdu 610042,China
4. TCM Hospital of Mianyang City,Mianyang 621000,China
5. People's Hospital of Sichuan Province,Chengdu 610075,China
Abstract:BACKGROUND: Bell's palsy involves acute facial paralysis due to inflammation of the facial nerve. Acupuncture and moxibustion (acu-moxi) is beneficial in treating facial palsy. In order to verify the efficacy of acu-moxi on Bell's palsy, a randomized single-blind, multicenter clinical trial was performed. METHODS: A total of 480 patients from four clinical centers were involved in this trial, of whom 439 completed the trial and 41 did not. All patients were randomly assigned to either the control group or to one of two treatment groups. The control group was treated with prednisone, vitamin B1, vitamin B12, and dibazole; the treatment groups were treated either with acu-moxi alone or in combination with prednisone, Vitamin B1, vitamin B12, and dibazole. Symptoms and signs, the House-Brackmann scale, and facial disability index (FDI) scores were assessed and determined both pre- and post-treatment to evaluate the effectiveness of the treatment methods. RESULTS: The characteristics of the control and two treatment groups were comparable without statistically significant differences before treatment. There were significant differences between the control and treatment groups after treatment (chi(2) = 15.265, P = 0.018). According to evaluations based on the House-Brackmann scale and FDI scores, the effectiveness of treatment in the two treatment groups was better than in the control group and was most effective in patients receiving acu-moxi treatment alone (Z = -2.827, P = 0.005). CONCLUSION: The efficacy of acu-moxi treatment for Bell's palsy is verified scientifically.
Keywords:acupuncture and moxibustion  Bell's palsy  multicenter trial  randomized controlled trial  House-Brackmann scale  FDI score
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