| 老年高尿酸血症与糖尿病前期及胰岛素抵抗的关系 |
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| 引用本文： | 蒋升,李素华.老年高尿酸血症与糖尿病前期及胰岛素抵抗的关系[J].中国全科医学,2009,12(1). |
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| 作者姓名： | 蒋升 李素华 |
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| 作者单位： | 1. 新疆医科大学第一附属医院内分泌科,新疆乌鲁木齐市,830054
2. 新疆医科大学第一附属医院肾病科,新疆乌鲁木齐市,830054 |
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| 摘 要： | 目的 探讨老年高尿酸血症(HUA)与糖尿病前期(PDM)及胰岛素抵抗(IR)的关系.方法 选择74例HUA合并PDM的老年患者(HUA组)和56例血尿酸水平正常的老年PDM患者(CG组).根据血糖水平再将两组患者分别分为空腹血糖受损(IFG)组和糖耐量异常(IGT)组.比较HUA组和CG组患者的空腹血糖(FPG)、空腹胰岛素(FINS)、糖耐量试验2 h血糖(2 hPG),计算并比较胰岛素抵抗指数(HOMA-IR)和胰岛素敏感指数(ISI).结果 HUA组血尿酸、FPG水平及HOMA-IR、ISI与CG组比较,差异有统计学意义(P＜0.05).HUA-IFG组血尿酸、FINS水平及HOMA-IR与CG-IFG组比较,差异有统计学意义(P＜0.05).HUA-IGT组血尿酸及2 hPG水平与CG-IGT组比较,差异亦有统计学意义(P＜0.05).血尿酸水平与FPG、FINS及HOMA-IR呈正相关(P＜0.05),与ISI呈负相关(P＜0.05).结论 HUA与胰岛素抵抗关系密切;HUA患者易合并IGT和(或)IFG.
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| 关 键 词： | 高尿酸血症 糖尿病前期 胰岛素抵抗 |
Relationship between Hyperuricemia and Pre-diabetes,Insulin Resistance in Senile Patients |
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| JIANG Sheng,LI Su-hua.Relationship between Hyperuricemia and Pre-diabetes,Insulin Resistance in Senile Patients[J].Chinese General Practice,2009,12(1). |
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| Authors: | JIANG Sheng LI Su-hua |
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| Institution: | JIANG Sheng,LI Su-hua.The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China |
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| Abstract: | Objective To explore the relations between hyperuricemiaand pre-diabetes(PDM),insulin resistance(IR) in senile patients.Methods Totally 74 senile patients with hyperuricemia and PDM(hyperuricemia group) and 56 senile patients with PDM and with normal serum uric acid(control group) were selected,then according to the levels of blood sugar the two groups were again divided as impaired fasting glucose subgroup and impaired glucose tolerance subgroup respectively.The levels of fasting plasma glucose(FPG),fastin... |
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| Keywords: | Hyperuricemia Pre-diabetes Insulin resistance |
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