| 经鼻持续正压通气治疗妊娠晚期合并阻塞性睡眠呼吸暂停低通气综合征的临床研究 |
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| 引用本文： | 崔小川,李翀,张希龙.经鼻持续正压通气治疗妊娠晚期合并阻塞性睡眠呼吸暂停低通气综合征的临床研究[J].中国全科医学,2011,14(1). |
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| 作者姓名： | 崔小川 李翀 张希龙 |
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| 作者单位： | 1. 南京医科大学第一附属医院呼吸科,江苏省南京市,210029
2. 苏州大学第三附属医院呼吸科 |
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| 基金项目： | 常州市卫生局青年人才科技项目(QN200804) |
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| 摘 要： | 目的分析妊娠合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)发病相关因素。观察自动调节经鼻持续气道正压通气(nCPAP)治疗妊娠合并OSAHS的临床疗效。方法比较21例对照组及24例OSAHS组患者的年龄、身高、体质指数(BMI)、颈围(NC)的差异;并对OSAHS组的呼吸暂停低通气指数(AHI)与年龄、身高、BMI、NC之间进行相关分析。对OSAHS组患者进行nCPAP治疗,并对比治疗前、治疗30d时的AHI、最低血氧饱和度(LSaO2)和最长呼吸暂停时间的变化。结果 OSAHS组患者和对照组的BMI、颈围间差异均有统计学意义(P<0.05),年龄、身高间差异均无统计学意义(P>0.05)。OSAHS组的AHI与BMI、颈围相关系数分别为0.603、0.696,呈正相关(P<0.01)。与治疗前相比,OSAHS患者治疗30d时的AHI、最长呼吸暂停时间均显著降低,差异有统计学意义(P<0.01),LSaO2显著升高,差异有统计学意义(P<0.01)。结论妊娠合并OSAHS患者年龄、BMI、颈围偏大,与AHI具有良好的相关性,测量颈围和BMI简单易行,可以作为预测OSAHS的初步筛选指标。nC-PAP治疗妊娠...
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| 关 键 词： | 妊娠 阻塞性睡眠呼吸暂停低通气综合征 经鼻持续正压通气 |
Nasal Continuous Positive Airway Pressure Treatment for Women with Obstructive Sleep Apnea Hypopnea Syndrome at Late Trimester of Pregnancy |
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| CUI Xiao-chuan,LI Chong,ZHANG Xi-long.Nasal Continuous Positive Airway Pressure Treatment for Women with Obstructive Sleep Apnea Hypopnea Syndrome at Late Trimester of Pregnancy[J].Chinese General Practice,2011,14(1). |
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| Authors: | CUI Xiao-chuan LI Chong ZHANG Xi-long |
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| Institution: | CUI Xiao-chuan,LI Chong,ZHANG Xi-long.Department of Respirology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China |
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| Abstract: | Objective To analyze the possible factors associated with the development of obstructive sleep apnea hypopnea syndrome (OSAHS) in women at late trimester of pregnancy and to observe the efficacy of nasal continuous positive airway pressure (nCPAP) treatment for their OSAHS.Methods Twenty one normal pregnant women (control group) and twenty four pregnant women with OSAHS (OSAHS group) were recruited and their age,body height,body mass index (BMI) and neck circumference (NC) were compared between the two grou... |
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| Keywords: | Obstructive sleep apnea hypopnea syndrome Pregnancy Continuous positive airway pressure |
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