| 口服加巴喷丁联合硬膜外药物注射治疗带状疱疹后神经痛的临床效果分析 |
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| 引用本文： | 段红光,杨远滨,郭玉娜,岳建宁,倪家骧.口服加巴喷丁联合硬膜外药物注射治疗带状疱疹后神经痛的临床效果分析[J].中国全科医学,2011,14(30). |
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| 作者姓名： | 段红光 杨远滨 郭玉娜 岳建宁 倪家骧 |
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| 作者单位： | 1. 首都医科大学宣武医院康复科,北京市,100053
2. 首都医科大学宣武医院疼痛科,北京市,100053 |
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| 摘 要： | 目的对比分析口服加巴喷丁联合硬膜外药物注射及单纯口服加巴喷丁对带状疱疹后神经痛的治疗效果。方法选择带状疱疹后神经痛患者74例,随机分为A、B两组,A组患者口服加巴喷丁胶囊联合硬膜外药物注射;B组患者仅口服加巴喷丁胶囊。分别于治疗前和治疗后7、15、30 d时对A组和B组的患者采用视觉模拟(VAS)评分及威斯康星简要疼痛目录评分进行评价,并观察两种治疗方法的并发症和药物的不良反应,以及需要增加镇痛措施的情况。结果治疗后两组患者7、15、30 d VAS评分及威斯康星简要疼痛目录评分比较,差异均有统计学意义(P<0.05),且组内不同时间点评分比较差异有统计学意义(P<0.05)。A组有1例穿刺部位疼痛较重,经局部注射治疗后缓解;发生头晕3例、嗜睡3例、恶心4例及口干2例。B组发生头晕8例、嗜睡5例、恶心5例及口干3例。A组有8例患者因效果欠佳,临时口服曲马朵缓解疼痛,共口服34次,总剂量2 750 mg。B组有14例患者加用曲马朵,共口服69次,总剂量5 650 mg。结论两种治疗方法对带状疱疹后神经痛均有一定的效果,口服加巴喷丁联合硬膜外药物注射治疗效果更佳,能迅速减轻早期带状疱疹后神经痛。
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| 关 键 词： | 注射 硬膜外 加巴喷丁 神经痛 带状疱疹后 |
Clinical Effects of Gabapentin Combined with Epidural Block in Treatment of Post-Herpetic Neuralgia |
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| DUAN Hong-guang,YANG Yuan-bin,GUO Yu-na,et al..Clinical Effects of Gabapentin Combined with Epidural Block in Treatment of Post-Herpetic Neuralgia[J].Chinese General Practice,2011,14(30). |
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| Authors: | DUAN Hong-guang YANG Yuan-bin GUO Yu-na |
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| Institution: | DUAN Hong-guang,YANG Yuan-bin,GUO Yu-na,et al.Department of Rehabilitation and Pain Management,Xuanwu Hospital,Capital Medical University,Beijing 100053,China |
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| Abstract: | Objective To explore the curative effects of gabapentin,with or without epidural block,in the treatment of post-herpetic neuralgia and to evaluate the clinical outcomes.Methods A total of 74 patients with post-herpetic neuralgia were divided randomly into two groups:group A and group B.Patients were treated with gabapentin with(group A) or without epidural block(group B).Verbal analogue scale(VAS) and Wisconsin brief pain inventory were used for the evaluation of pain before treatment and on the 7th,15th,an... |
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| Keywords: | Injections epidural Gabapentin Neuralgia post-herpetic |
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