我国轻度认知障碍研究热点分析及展望

背景　随着人口老龄化进程的加快,包括痴呆在内的老年人健康问题日益突出。轻度认知障碍作为阿尔茨海默病的临床前阶段,早已成为研究者关注的热点。但是目前尚缺乏对我国轻度认知障碍研究热点的整理与分析。目的　分析2008-2018年我国轻度认知障碍研究的热点,了解该领域的现状和发展趋势。方法　2019年6月,以“轻度认知障碍”为关键词,采用主题检索的方式,在中国期刊网全文数据库（CNKI）中进行检索,检索时间为2008-2018年,文献来源类别限定为SCI来源文献、EI来源期刊、核心期刊、中文社会科学引文索引（CSSCI）以及中国科学引文数据库（CSCD）。采用中医药数据关联分析平台（XMiner软件）、SPSS 22.0统计学软件、Excel软件对关键词进行词频分析和共词聚类分析。结果　最终纳入符合标准的文献413篇,获得高频关键词41个（g=41）。通过共词聚类分析总结出2008-2018年我国轻度认知障碍的7个研究热点,分别为轻度认知障碍的病因学研究、神经心理评估及筛查研究、诊断及分类研究、干预研究、流行病学研究、精神行为症状研究、生物标志物及中医证候研究。结论　2008-2018年我国轻度认知障碍的研究热点分别为轻度认知障碍的病因学研究、神经心理评估及筛查研究、诊断及分类研究、干预研究、流行病学研究、精神行为症状研究、生物标志物及中医证候研究,该分析结果有助于广大卫生服务人员了解该领域的现状和发展趋势,且对其今后的研究方向有一定的指导作用。

Analysis and Prospect of Hot Topics in Mild Cognitive Impairment Research in China

Background　With the acceleration of population aging,the health problems of the elderly,including dementia,are increasingly prominent.Mild cognitive impairment,the preclinical stage of Alzheimer's disease,has long been a focus of researchers.However,there is a lack of studies concerning the summary or analysis of hot topics of mild cognitive impairment in China.Objective　To analyze the hot topics in mild cognitive impairment research in China from 2008 to 2018,to provide assistance for understanding the current status and development trend of this field.Methods　In June 2019,we searched the CNKI database with the key word "mild cognitive impairment" and subject retrieval as well as source categories limited to SCI and EI source journals,core journals,CSSCI and CSCD for studies about mild cognitive impairment in China during 2008 to 2018.TCM correlation analysis platform-based XMiner software,SPSS 22.0 and Excel-based software were used to perform word frequency and co-word analyses of the key words.Results　Finally,413 studies with 41 high-frequency key words（g=41） were included.Seven hot topics were identified by co-word analysis,including etiology,neuropsychological assessment and screening,diagnosis and classification,intervention,epidemiology,behavioral and psychological symptoms,biomarkers and TCM syndrome of mild cognitive impairment.Conclusion　The hot topics in mild cognitive impairment research in China from 2008 to 2018 are etiology,neuropsychological assessment and screening,diagnosis and classification,intervention,epidemiology,behavioral and psychological symptoms,biomarkers and TCM syndrome of mild cognitive impairment.The results are helpful for healthcare providers to understand the current situation and development trend of this field,with guidance for future research direction.