| 云南少数民族和汉族慢性肾脏病肾小球滤过率评估方程的临床研究 |
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| 引用本文： | 翁敏,杨荆,张健皎,白云凯.云南少数民族和汉族慢性肾脏病肾小球滤过率评估方程的临床研究[J].中国全科医学,2010,13(8):813-816. |
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| 作者姓名： | 翁敏 杨荆 张健皎 白云凯 |
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| 作者单位： | 昆明医学院第一附属医院肾内科,云南省昆明市,650032 |
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| 摘 要： | 目的 评价肾小球滤过率(GFR)评估方程在云南少数民族和汉族慢性肾脏病(CKD)患者中的适用性.方法 选择174例少数民族和汉族CKD患者,将Cockcroft-Gault方程、MDRD7 方程和简化MDRD方程估算的GFR值用体表面积(BSA)标准化,与BSA标准化的~(99m)Tc-DTPA测得的GFR在不同CKD分期进行比较.结果 方程估算的GFR与~(99m)Tc-GFR(sGFR)呈正相关(P＜0.05),相关性最好的是 MDRD7方程;受试者工作特征(ROC) 曲线下的面积也表明MDRD7方程诊断效率最好,但是MDRD7方程用于我国人群时出现高估或低估偏差.结论 经统计数理方法与临床分期相结合、比较,最终建立了用7GFR值推算sGFR值的校正式:sGFR=7GFR×1.25-11.72.
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| 关 键 词： | 肾小球滤过率 评估方程 慢性肾脏病 少数民族 汉族 |
GFR Estimation Equations in Minorities and Han Nationality with Chronic Kidney Disease |
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| WENGMin,YANGJing,ZHANGJian-jiao,etal.GFR Estimation Equations in Minorities and Han Nationality with Chronic Kidney Disease[J].Chinese General Practice,2010,13(8):813-816. |
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| Authors: | WENGMin YANGJing ZHANGJian-jiao etal |
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| Institution: | WENG+Min,YANG+Jing,ZHANG+Jian-jiao,et+al.Department+of+Nephrology,First+Affiliated+Hospital+of+Kunming+Medical+College,Kunming+650032,China |
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| Abstract: | Objective To estimate the applicability of GFR (glomerular filter rate) equations in minorities and Han with chronic kidney disease(CKD) in Yunnan Province.Methods The BSA-standardized GFR values estimated with equations Cockcroft-Gault,MDRD7 and simplified MDRD were compared with those measured with 99mTc-DTPA in 174 CKD patients (included Han and minorities) at different stages.Results The equation-estimated GFR was positively correlated with 99mTc-GFR(sGFR)( P<0.05),MDRD7 equation with the highest correl... |
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| Keywords: | Glomeralar filtration rate Estimate equation Chronic kidney disease Minority Han nationality |
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