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最小临床重要差值在支气管扩张症疗效测评工具中的应用与思考
引用本文:关佳瑞,任嘉铭,谢洋,张彭.最小临床重要差值在支气管扩张症疗效测评工具中的应用与思考[J].中国全科医学,2022,25(30):3739.
作者姓名:关佳瑞  任嘉铭  谢洋  张彭
作者单位:1.450046 河南省郑州市,河南中医药大学2.450000 河南省郑州市,河南中医药大学第一附属医院呼吸科
基金项目:国家自然科学基金重点项目(81830116); 国家重点研发计划(2018YFC1704806); 河南省自然科学基金优秀青年科学基金项目(212300410056); 河南省科技攻关计划(172102310200); 河南省第二批中医药拔尖人才项目(豫卫中医函〔2021〕15号)
摘    要:支气管扩张症(BE)发病率逐年增高,给患者及家庭造成了沉重的经济负担,对患者生存质量影响较大。随着患者报告结局(PRO)在BE临床应用中的增多,研究者不再只关注其统计学差异(P<0.05),其最小临床重要差值(MCID)也逐渐成为研究热点。当前对BE-PRO测评工具的MCID研究还缺乏相关数据,本文概述了MCID在BE-PRO测评工具中的研究现状,以期为BE相关临床疗效评价提供量化标准及参考依据。

关 键 词:支气管扩张症  患者报告结局  生活质量  最小临床重要差值  测评工具  量表  
收稿时间:2022-04-10

Application of Minimal Clinically Important Difference in Outcome Assessment Tools for Bronchiectasis Treatment
Jiarui GUAN,Jiaming REN,Yang XIE,Peng ZHANG.Application of Minimal Clinically Important Difference in Outcome Assessment Tools for Bronchiectasis Treatment[J].Chinese General Practice,2022,25(30):3739.
Authors:Jiarui GUAN  Jiaming REN  Yang XIE  Peng ZHANG
Institution:1. Henan University of Chinese Medicine, Zhengzhou 450046, China2. Department of Respiratory Medicine, the First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China
Abstract:Increased bronchiectasis (BE) prevalence has imposed heavy economic burden on patients and their families, greatly affecting the quality of life of patients. With increased use of patient reported outcome (PRO) in bronchiectasis treatment assessment, researchers not only focus on statistical pre-and post-treatment differences (P<0.05) , but also pay attention to minimal clinically important difference (MCID) . Currently, there is still a lack of relevant data about MCID in BE-PRO assessment tools. We reviewed the latest research on the use of MCID in BE-PRO assessment tools, aiming at providing a quantitative basis for outcome assessment in BE treatment.
Keywords:Bronchiectasis  Patient reported outcome  Quality of life  Minimal clinically important difference  Measurement instrument  Scale  
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