恶性嗜铬细胞瘤19例诊断与治疗分析

目的：对恶性嗜铬细胞瘤临床诊治进行回顾分析，以提高其诊断和治疗水平。方法：临床有高血压或腹部疼痛不适症状18例，无症状1例。尿儿茶酚胺(CA)、尿香草基苦杏仁酸(VMA)阳性率分别为31．6％、63．2％。CT、磁共振成像(MR)等检查证实腹膜后病灶多呈异位或浸润性生长。19例均在全麻下行手术治疗。结果：12例完整切除肿瘤，7例部分切除或包膜内剜除。完整切除病灶者术后情况良好，随访1～5年未出现复发。结论：对恶性嗜铬细胞瘤应结合临床、手术及病理以早期诊断，肿瘤根治切除能获得良好的治疗效果。

Diagnosis and Treatment for Malignant Pheochromocytom:a Report of 19 Cases

To improve the diagnosis and the treatment with malignant pheochromocytoma. Methods: Eighteen eases had the symptom of hypertension or abdomen pain, and one had no symptom. The positive rate of the urine catecholamine and VMA was 31. 6%, 63. 2% respectively. CT, MR revealed the most tumor retroperitoneal were ectopic or growing invasively. Results: All patients received the operation and twelve were excised the tumor fully. Seven were excised the tumor partially or cut out under the envelope. The patients that received radical resection of tumors were followed up 1 to 5 years with no recurrence. Conclusion: Diagnosis of malignant pheochromocytoma at early stage needs the data from clinic, operation and pathology. Radical resection of the tumor can achieve good effects.