| 应用BED-CEIA方法估算江苏省男男性行为人群艾滋病病毒感染的新发感染率 |
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| 引用本文： | 胡海洋,沈〓圣,还锡萍,闫红静,肖〓瑶,蒋〓岩.应用BED-CEIA方法估算江苏省男男性行为人群艾滋病病毒感染的新发感染率[J].南京医科大学学报,2010(4):467-471. |
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| 作者姓名： | 胡海洋 沈〓圣 还锡萍 闫红静 肖〓瑶 蒋〓岩 |
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| 作者单位： | 江苏省疾病预防控制中心性病与艾滋病防制所;中国疾病预防控制中心;性病艾滋病预防控制中心;国家艾滋病参比实验室; |
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| 基金项目： | 江苏省社会发展计划资助项目(BE2009685) |
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| 摘 要： | 目的:了解江苏省男男性行为人群(MSM)艾滋病病毒(HIV)的感染状况,估算HIV在该人群中的新发感染率。方法:对2008年国家男男性行为人群艾滋病综合防治试点工作的710份样本,进行HIV-1初筛、复检及确证试验,检出的HIV-1阳性样本,再应用BEDHIV-1IgG捕获酶免疫法(BED-CEIA)检出其中的新发感染样本,进而估算该人群的HIV-1新发感染率。结果:710份样本共检出HIV-1阳性样本40份,HIV-1感染率为5.63%;40份HIV-1阳性样本中的23份被判定为新发感染,感染者中新发感染的比例高达57.5%;校正后的HIV-1新发感染率为7.54%(95%CI:4.46%～10.62%)。结论:HIV-1在江苏省MSM人群中的流行已经处于较高水平且新发感染状况不容乐观,必须加大防控力度。
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| 关 键 词： | 艾滋病病毒 BED-CEIA 新发感染率 男男性行为人群 |
| 收稿时间： | 2009/11/17 0:00:00 |
Estimation of HIV-1 incidence of MSM in Jiangsu Province with BED-CEIA assay |
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| HU Hai-yang,SHEN Sheng,HUAN Xi-ping,YAN Hong-jing,XIAO Yao and JIANG Yan.Estimation of HIV-1 incidence of MSM in Jiangsu Province with BED-CEIA assay[J].Acta Universitatis Medicinalis Nanjing,2010(4):467-471. |
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| Authors: | HU Hai-yang SHEN Sheng HUAN Xi-ping YAN Hong-jing XIAO Yao and JIANG Yan |
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| Institution: | Section of AIDS/STD Control and Prevention/a>;Jiangsu Center for Disease Control and Prevention/a>;Nanjing 210009/a>;1National AIDS Reference Laboratory/a>;National Center for AIDS/STD Control and Prevention/a>;Chinese Center for Disease Control and Prevention/a>;Beijing 100050/a>;China |
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| Abstract: | Objective:To understand HIV infection of men who have sex with men (MSMs) in Jangsu Province,and estimate the annual HIV incidence of MSMs. Methods:710 samples from national pilot work of HIV/AIDS comprehensive prevention and care among MSMs in 2008 were tested to find HIV-1 seropositive samples.BED HIV-1 IgG capture enzyme immunoassay (BED-CEIA) was used to find recent HIV-1 infections in HIV-1 seropositive samples,and the annual HIV-1 incidence of MSMs was estimated. Results:40 samples were HIV-1 seroposi... |
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| Keywords: | HIV BED-CEIA incidence MSMs |
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