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| Chrysanthemum indicum linnéextracts attenuate the mitogenic effect of epinephrine on human HCC cells | |
| 作者姓名： | Aihua Yuan Zongfang Xinqiu Li Shanyong Yi Shukui Wang Kaiwang Shi Jianmin Bian |
| 作者单位： | Aihua Yuan(Department of General Surgery, Second Affiliated Hospital of Medical College of Xi' an Jiaotong University, Xi' an, China;Department of General Surgery, Nanfing First Hospital Affiliated to Nanfing Medical University, Nanjing, China);Zongfang Li(Department of General Surgery, Second Affiliated Hospital of Medical College of Xi' an Jiaotong University, Xi' an, China);Xinqiu Li(Department of Hepatobiliary Surgery, First Affiliated Hospital of Medical College of Xi' an Jiaotong University, Xi' an, China);Shanyong Yi(Department of Cancer Center, First Affiliated Hospital of Medical College of Xi' an Jiaotong University, Xi' an, China);Shukui Wang,Kaiwang Shi,Jianmin Bian(Department of General Surgery, Nanfing First Hospital Affiliated to Nanfing Medical University, Nanjing, China) |
| 摘 要： | Objective: To investigate the stimulatory effect of epinephrine(Epi) and the antagonistic effect of Chrysanthemum indicum Linné extracts (CILE) on Epi-induced growth of human hepatocellular carcinoma(HCC) cells. Methods: The stimulatory effect of Epi and inhibitory effect of CILE on the growth of HepG2 and MHCC97H cells were investigated using a proliferation assay in correlation with βadrenergic receptor(β 2-AR) blockade, a MEK1/MEK2 inhibitor, and assessment of MAPK/ERK1/2 intracellular activity. Results:... |
| 关 键 词： | Chrysanthemum indicum Linnéextracts epinephrine extracellular signal-regulated kinase 1/2 hepatocellular carcinoma |
| 收稿时间： | 2009/4/16 0:00:00 |
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