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白内障超声乳化吸出术对角膜内皮细胞损伤机制的实验性研究
引用本文:袁松涛,谢莉娜,刘庆淮.白内障超声乳化吸出术对角膜内皮细胞损伤机制的实验性研究[J].南京医科大学学报,2003,23(4):309-311,321.
作者姓名:袁松涛  谢莉娜  刘庆淮
作者单位:南京医科大学第一附属医院眼科,南京医科大学第一附属医院眼科,南京医科大学第一附属医院眼科 江苏 南京 210029,江苏 南京 210029,江苏 南京 210029
基金项目:江苏省科委社会发展基金资助项目(BS99045-1)
摘    要:目的:评估白内障超声乳化吸出术中各个损伤因素在角膜内皮细胞损伤中所占的比率。方法:14只家猫28眼分为4组,处理因素为超声能量、超声乳化摘除或不摘除晶体,以不同的能量摘除晶体。手术前后分别测量中央角膜内皮细胸密度。结果:不摘除晶体而单纯释放超声能量组的角膜内皮细胞密度手术前后没有统计学差异,摘除晶体组的角膜内皮细胞密度均下降,且所使用能量的越大角膜内皮细胞密度下降程度越大。结论:白内障超声乳化手术中,晶体核碎片引起角膜内皮损伤是首要因素,而其他因素在正常的手术过程中对角膜内皮细胞的损伤很小。

关 键 词:白内障  超声乳化吸出术  角膜内皮细胞  
文章编号:1007-4368(2003)04-0309-04

An Experimental Study on the Mechanism of Corneal Endothelial Lesion during Pha- coemulsification and Aspiration
YUAN Song-tao,XIE Li-na,LIU Qing-huai.An Experimental Study on the Mechanism of Corneal Endothelial Lesion during Pha- coemulsification and Aspiration[J].Acta Universitatis Medicinalis Nanjing,2003,23(4):309-311,321.
Authors:YUAN Song-tao  XIE Li-na  LIU Qing-huai
Abstract:Objective:To evaluate the proportions of corneal endothelial cell lesion caused by different factors during phacoemulsifi-cation and aspiration. Methods: Fourteen cats(28 eyes) were divided into four groups. The processed factors were ultrasonic power, lens extraction by phacoemulsification or not, and lens extraction using different level of ultrasonic power. The density of central corneal endothelial cells was measured before and after operation. Results: In releasing ultrasonic power only without lens extraction group, there was no significant difference in density of central corneal endothelial cells between pre-operation and post-operation, but in the lens extraction group, there was significant difference in density of central corneal endothelial cells, and the higher level of ultrasonic power was used, the more the central corneal endothelial cells density decreased through operation. Conclusion: The primary factor that causes corneal endothelial lesion during phacoemulsification and aspiration procedure is debris of lens nucleus, and the other factors cause the lesion of corneal endothelium in normal operations just in very small degree.
Keywords:cataract  phacoemulsification  corneal endothelial cells  cat
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