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1株泛耐药铜绿假单胞菌耐药基因研究
引用本文:糜祖煌,秦玲.1株泛耐药铜绿假单胞菌耐药基因研究[J].世界感染杂志,2008,8(4):280-282.
作者姓名:糜祖煌  秦玲
作者单位:江苏省无锡市克隆遗传技术研究所,江苏无锡214026
摘    要:目的了解1株泛耐药铜绿假单胞菌(PDRPA)耐药基因携带状况。方法采用PCR检测该株PDRPA菌44种基因。结果该株PDRPA菌携带TEM-1、OXA.10、PER-1、aac(3)-Ⅱ、aac(6’)-Ⅱ、ant(3”)-Ⅰ、rmtB、sull、cmlA、intⅠ1、merA基因,且伴有oprD2缺失。结论该株PDRPA菌携带多种耐药基因是泛耐药原因。

关 键 词:泛耐药铜绿假单胞菌  耐药基因

Analysis on resistant genes in a pan-drug resistant P. aeruginosa
MI Zu-huang,QIN Ling.Analysis on resistant genes in a pan-drug resistant P. aeruginosa[J].World Journal of Infection,2008,8(4):280-282.
Authors:MI Zu-huang  QIN Ling
Institution:(Wuxi Clone Gen-Tech Istitute, Wuxi, 214026, China)
Abstract:Objective To investigate the resistance gene in a pan-drug resistant E aeruginosa. Methods The 44 kinds of genes were detected by PCR. Results There are genes of TEM-1, OXA-10, PER-1, aac(3)-Ⅱ, aac(6')-Ⅱ, ant(3")- Ⅰ, rmtB, sull, cmlA, int Ⅰ1 and merA in this strain, and with the deletion of oprD2 gene. Conclusions In this strain, many types of resistance genes are the reasons for pan-drug resistance.
Keywords:pan-drug resistant E aeruginosa: resistant gene
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