| 大肠埃希菌、肺炎克雷伯菌连续分离株β-内酰胺酶基因研究 |
| |
| 引用本文： | 糜祖煌,钱小毛,黄支密.大肠埃希菌、肺炎克雷伯菌连续分离株β-内酰胺酶基因研究[J].世界感染杂志,2008,8(2):101-105. |
| |
| 作者姓名： | 糜祖煌 钱小毛 黄支密 |
| |
| 作者单位： | [1]无锡市克隆遗传技术研究所,江苏无锡214026 [2]绍兴第二人民医院,浙江绍兴312000 [3]解放军98医院,浙江湖州313000 |
| |
| 摘 要： | 目的了解大肠埃希菌、肺炎克雷伯菌连续分离株β-内酰胺酶基因存在状况。方法采用PCR检测浙江地区二家医院大肠埃希菌、肺炎克雷伯菌连续分离株21种β-内酰胺酶基因。结果检出TEM、SHV、LEN、CTX-M-1 cluster、CTX-M-9 cluster、OXA-1 cluster、OXA-10 cluster、LAP、DHA、ACT-1等β-内酰胺酶基因，并在国内外首次从大肠埃希菌、肺炎克雷伯菌中发现LAPβ-内酰胺酶基因。结论浙江地区二家医院大肠埃希菌、肺炎克雷伯菌连续分离株β-内酰胺酶基因携带率高。存在新的β-内酰胺酶基因（LAP）。
|
| 关 键 词： | 大肠埃希菌 肺炎克雷伯菌 β-内酰胺酶 |
Study on the β-lactamase genes of continuously isolated Escherichia coli and Klebsiella pneumoniae strains |
| |
| Institution: | MI Zu-huang, QIAN Xiao-mao, HUANG Zhi-mi (Wuxi Clone Gen-Tech Istitute, Wuxi, Jiangsu, 214026, China) |
| |
| Abstract: | Objective In order to understand β-lactamase gene status in continuously isolated Escherichia coli and Klebsiella pneumoniae strains. Methods 21 kinds of β-lactamase genes were detected by PCR in two Zhejiang hospitals. Results There were TEM, SHV, LEN, CTX-M-1 cluster, CTX-M-9 cluster, OXA-1 cluster, OXA-10cluster, LAP, DHA and ACT-1 genes in two Zhejiang hospitals. The LAP β-lactamase gene is found from Escherichia coli and Klebsiella pneumoniae in world for the first time. Conclusions The β-lactamase gene carrying rate is high in continuously isolated Escherichia coli and Klebsiella pneumoniae strains in two Zhejiang hospitals. There is new β-lactamase gene （LAP）. |
| |
| Keywords: | Escherichia coli Klebsiella pneumoniae β-lactamase gene |
| 本文献已被 维普 等数据库收录！ |
|
