脑卒中后疲劳相关因素及影像学特征的研究

目的 探讨脑卒中后疲劳(PoSF)的相关因素及影像学特征.方法 研究对象为98例脑梗死患者,使用个人强度目录、抑郁自评量表(SDS)、牛津社区卒中计划、徒手肌力检查、斯堪的纳维亚卒中量表、Rankin修订量表以及核磁共振结果 进行评估.结果 脑卒中后疲劳的发生率为42.9%,SDS分数、年龄、睡眠状况差和最差肢体肌力是脑卒中后疲劳的显著贡献因子,logistic回归分析得到P值分别为0.003,0.020,0.021,0.029.额叶萎缩位于显著性边缘,P值为0.066,回归方程的适配度P值=0.01.结论 脑卒中后疲劳与SDS分数、年龄、睡眠状况和肢体功能障碍密切相关,额叶萎缩、深层白质变性等因素对卒中患者的疲劳也有一定影响.

A study on correlate factors and characters of imagine of post stroke fatigue in stroke patients

Objective To investigate the correlate factors and characteristics of magnetic resonance images in stroke patients.Methods To investigate Checklist Individual Strength,Zung Self-rating Depression Scale,Oxfordshire Community Stroke Project,manual muscle testing,Scandinavian Stroke Scale,Modified Rankin Scale and results of magnetic resonance images in 98 stroke patients.Results The incidence of post stroke fatigue was 42.9%.Score of SDS,age,sleep condition and muscle strength were significant contribution factors(P＜0.05 or P＜0.01) ,and frontal lobe atrophy was at the edge of significance (P=0.066).Conclusion Post stroke fatigue correlated well with score of SDS,age,sleeping and limbs disturbance,while frontal lobe atrophy and deep white matter changes contributed to influence in post stroke fatigue as well.