持续非卧床腹膜透析对尿毒症患者微量元素的影响

目的 探讨持续非卧床腹膜透析（CAPD）对尿毒症患者微量元素的影响。方法 用火焰及无火焰原子吸收法检测30例尿毒症患者行持续非卧床腹膜透析前及透析1月后血清铜、锌、铁的含量及腹膜透析透出液中铜、锌、铁、钙、镁、磷、钾元素的含量，分析腹膜透析前后尿毒症患者血清及透出液中微量元素的变化。结果 尿毒症患者透析后血清铁及锌的浓度均明显高于透析前（P〈0．05），而血清铜透析前后无明显差异（P〉0．05）。腹膜透析透出液中铜、锌、镁、钾、钙、磷含量透析前后有显著性差异（P〈0．05），而腹膜透析透出液中铁浓度透析前后无明显差异（P〉0．05）。结论 经CAPD治疗后尿毒症患者铜、锌、铁、磷、钾的异常代谢可得到部分纠正。

The Influence of Continuous Ambulatory Peritoneal Dialysis on the Trace Elements in Uremic Patients

Objective To explore the influence of continuous ambulatory peritoneal dialysis(CAPD) on the trace-elements in uremic patients.Methods 30 CAPD patients were included in the study.Analyze the Cu~(+2),Zn~(+2),Fe~(+2)in serum and Cu~(+2),Zn~(+2),Fe~(+2),Ca~(+2),Mg~(+2),P~(+3),K~(+1) in dialysate before and one month after CAPD.Results In serum,the Zn~(+2) and Fe~(+2) before CAPD were higher than those after CAPD(P<0.05),while the Cu~(+2) was no statistical difference in uremic patients.In dialysate,there were statistical differences in Cu~(+2),Zn~(+2),Mg~(+2),K~(+1),Ca~(+2)and P~(+3) in CAPD patients pre-and-post CAPD(P<0.05),while Fe~(+2) was no difference(P<0.05).Conclusion CAPD can improve the malcatabolism of Zn~(+2),Ca~(+2),Fe~(+2),P~(+3)and K~(+1) in uremic patients.