超声心动图监测孕中晚期胎儿心室Tei指数变化及其与子痫前期的关系

目的 超声心动图监测孕中晚期胎儿心室Tei指数变化情况,探讨其与子痫前期的关系。 方法 选择2012年12月-2015年12月金华市中心医院产科重度子痫前期孕妇70例作为A组,轻度子痫前期孕妇70例作为B组,同期正常孕妇220例作为C组。对所有孕妇进行超声心动图检查,观察正常孕妇不同孕周胎儿心室Tei指数,各组孕妇新生儿出生情况、心室功能指标、心室Tei指数,子痫前期孕妇胎儿右心室Tei指数和胎儿出生情况的相关性。 结果 在正常孕妇中,各孕周右心室的Tei指数高于左心室的Tei指数,但两者之间比较差异没有统计学意义(P>0.05)。A组新生儿出生体重、出生孕周均小于B组和C组(P<0.05),A组新生儿出生1 min和5min Apgar评分均小于B组和C组(P<0.05)。A组左心室射血分数和右心室射血分数低于C组(P<0.05);A组和B组左心室等容时间和右心室等容时间高于C组(P<0.05)。A组左心室Tei指数和右心室Tei指数高于B组和C组(P<0.05);B组左心室Tei指数和右心室Tei指数高于C组(P<0.05)。子痫前期新生儿的右心室Tei指数和胎儿的出生体重、出生孕周、1 min Apgar评分、5 min Apgar评分均呈负相关(P<0.05)。 结论 心室Tei指数能够评价胎儿心脏功能,子痫前期胎儿心功能有一定程度的损害,影响胎儿的预后,Tei指数检测对预测子痫前期胎儿预后有一定价值。 

Fetal cardiac Tei index change in second and third trimester by echocardiography and its relationship with preeclampsia

Objective To study the fetal ventricular Tei index changes by using echocardiography,and to explore its relationship with preeclampsia. Methods From December,2012 to December,2015,70 cases severe preeclampsia pregnant women (group A),70 cases mild preeclampsia pregnant women (group B) and 220 cases normal pregnant women (group C) in our hospital were recruited.All pregnant women were checked by echocardiography.The ventricular Tei index of different gestational weeks fetal of normal pregnant women was recorded,and the birth situation,index of ventricular function and Tei of each group were observed.The correlation between Tei of fetal in preeclampsia women and birth outcome was evaluated. Results In normal pregnancy,the right ventricle Tei index was higher than the left ventricle Tei index of each gestational age,but the difference was not statistically significant (P>0.05).The birth weight,gestational age of group A were less than that of group B and group C (P<0.05),the Apgar scores at 1 minute and 5 minute after the birth of group A were less than those of group B and group C (P<0.05).The left ventricular ejection fraction and right ventricular ejection fraction of group A were lower than that of group C (P<0.05);the left ventricular isovolumic time and right ventricular isovolumic time of group A and group B were higher than that of group C (P<0.05).the left ventricular Tei index and right ventricular Tei index of group A were higher than that of group B and group C (P<0.05);the left ventricular Tei index and right ventricular Tei index group B were higher than that of group C (P<0.05).The right ventricular Tei index of preeclampsia newborn were negatively correlated with fetal birth weight,gestational age,1 minute Apgar score,5 minutes Apgar score (P<0.05). Conclusion Ventricular Tei index can be used to evaluate fetal cardiac function.The cardiac function of preeclampsia fetus is usually with a certain degree of damage,which will affect fetal prognosis.Tei index has a certain value in predicting preeclampsia fetal prognosis.