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痰浊与肿瘤微环境的相关性探讨
引用本文:张慈安,魏品康,李勇进.痰浊与肿瘤微环境的相关性探讨[J].中西医结合学报,2010,8(3):215-219.
作者姓名:张慈安  魏品康  李勇进
作者单位:第二军医大学长征医院中医科,上海,200003
摘    要:肿瘤细胞由于生长迅速,能量代谢异常以及特定蛋白的自身调节,导致形成和维持一个不适合正常细胞生存的细胞微环境,同时这种微环境又保证了其发生、增殖、侵袭与转移。细胞生存的微环境主要由细胞间质及其所含成分参与构成,其对细胞内外物质传递及代谢的作用,与津液的滋润和濡养作用相似,而痰浊正是体内津液代谢异常导致的最主要病理产物。因此探讨痰浊与肿瘤细胞微环境的相关性。有助于阐明痰浊的物质基础,并且有可能成为中西医结合抗肿瘤研究的新切入点。

关 键 词:肿瘤微环境  痰浊  中西医结合  相关性

Discussion of the correlation between phlegm and tumor microenvironment
Ci-an ZHANG,Pin-kang WEI,Yong-jin LI.Discussion of the correlation between phlegm and tumor microenvironment[J].Journal of Chinese Integrative Medicine,2010,8(3):215-219.
Authors:Ci-an ZHANG  Pin-kang WEI  Yong-jin LI
Institution:(Department of Traditional Chinese Medicine, Changzheng Hospital, Second Military Medical University, Shanghai 200003 China)
Abstract:An abnormal microenvironment which is not fit tained due to rapid growth, abnormal energy metabolism cells. At the same time, the abnormal microenvironment for the living of normal cells is induced and main- and self-regulation of specific proteins of the tumor is the guarantee of the neoplastic transformation, proliferation, invasion and metastasis of tumor cells. The microenvironment mainly consists of interstitial cells and their components. There are correlations between the physiological role of body fluid and the physiological functions of microenvironment. Phlegm is the product of abnormal body fluid metabolism. So to discuss the correlations of them may contribute to clarifying the material base of phlegm and will further give new insight for integrated traditional Chinese and Western medicine in cancer research.
Keywords:tumor microenvironment  phlegm integrated traditional Chinese and Western medicine correlation
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