中晚期肺癌患者合并霉菌感染的中医证候危险因素分析

目的:探讨中晚期肺癌患者肺部霉菌感染与中医证候的关系.方法:应用logistic回归分析方法,对115例中晚期肺癌患者合并肺部霉菌感染的中医证候(气虚、阴虚、血虚、阳虚、血瘀、痰湿、痰热、湿热、寒湿、气滞、热毒)的危险因素进行回顾性临床研究.结果:中晚期肺癌患者有痰热证时其合并霉菌感染的危险度升高(P《0.01),而有热毒证时其合并霉菌感染的危险度亦明显升高(P《0.05).结论:中医的痰热证、热毒证的出现是中晚期肺癌患者合并霉菌感染的危险性信号.

Risk factors of traditional Chinese medical syndromes in moderate and advanced lung cancer patients with concurrent fungal pneumonia

Objective:To analyze the relationship between traditional Chinese medical syndromes and fungal pneumonia for moderate and advanced lung cancer patients. Methods: We retrospected 115 moderate and advanced lung cancer patients with different syndromes in traditional Chinese medicine (qi deficiency, yin deficiency, blood deficiency, yang deficiency, blood stasis, phlegm dampness, phlegm heat, damp heat, cold dampness, qi stagnation, heat toxin), who had the concurrent fungal pneumonia, and used regression analysis method to analyze the data. Results: When the patients had the phlegm heat syndrome, they got a significantly higher risk of having fungal pneumonia ( P <0. 01); and when they had the heat toxin syndrome, they also had a high risk of having fungal pneumonia( P <0. 05). Conclusion: The phlegm heat and heat toxin syndromes are the risk factors for moderate and advanced lung cancer patients having concurrent fungal pneumonia.