| AFP、CEA、CA199、CA125及CA153联合检测诊断原发性肝癌的价值研究 |
| |
| 引用本文： | 向丹丹,王丛.AFP、CEA、CA199、CA125及CA153联合检测诊断原发性肝癌的价值研究[J].罕少疾病杂志,2022,29(2):63-64,73. |
| |
| 作者姓名： | 向丹丹 王丛 |
| |
| 作者单位： | 南阳市第二人民医院医学遗传中心 河南南阳 473000 |
| |
| 摘 要： | 目的研究甲胎蛋白(AFP)、癌胚抗原(CEA)、糖类抗原-199(CA199)、糖类抗原-125(CA125)及糖类抗原-153(CA153)联合检测诊断原发性肝癌(PHC)的价值。方法选择2019年1月至2020年12月我院治疗的70例PHC患者并作为PHC组,同时选取同期在我院治疗的75例良性肝病患者并作为良性肝病组,选取同期到我院体检的健康人群70例作为对照组。采集三组患者晨起空腹静脉血4mL,采用化学发光法测定AFP、CEA、CA199、CA125及CA153水平。比较三组AFP、CEA、CA199、CA125及CA153水平,并计算AFP、CEA、CA199、CA125及CA153单项及联合诊断PHC的敏感度、特异度。结果PHC组AFP、CEA、CA199、CA125及CA153水平>良性肝病组>对照组,差异有统计学意义(P<0.05);AFP+CEA+CA199+CA125+CA153诊断PHC敏感度高于各单项指标检测结果,诊断PHC特异度高于AFP、CEA,差异有统计学意义(P<0.05)。结论PHC患者血清AFP、CEA、CA199、CA125及CA153水平呈高表达,联合检测上述指标有利于提升PHC诊断准确率,为临床诊治PHC提供帮助。
|
| 关 键 词： | 原发性肝癌 甲胎蛋白 癌胚抗原 糖类抗原-199 |
Study on the Value of AFP,CEA, CA199, CA125, and CA153 Combined Detection in the Diagnosis of Primary Liver Cancer |
| |
| XIANG Dan-dan,WANG Cong.Study on the Value of AFP,CEA, CA199, CA125, and CA153 Combined Detection in the Diagnosis of Primary Liver Cancer[J].Journal of Rare and Uncommon Diseases,2022,29(2):63-64,73. |
| |
| Authors: | XIANG Dan-dan WANG Cong |
| |
| Institution: | (Medical Genetics Center,Nanyang Second People's Hospital,Nanyang 473000,Henan Province,China) |
| |
| Abstract: | |
| |
| Keywords: | Primary Liver Cancer Alpha Fetoprotein Carcinoembryonic Antigen Sugar Antigen-199 |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
