| 骨髓增生异常综合征患者外周血肿瘤坏死因子活性变化与预后的关系 |
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| 引用本文： | 朱彦,金蓉珍,黄非,杨苏南,朱玲.骨髓增生异常综合征患者外周血肿瘤坏死因子活性变化与预后的关系[J].江苏大学学报(医学版),1996(4). |
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| 作者姓名： | 朱彦 金蓉珍 黄非 杨苏南 朱玲 |
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| 摘 要： | 采用生物学方法检测了１１例骨髓增生异常综合征（ＭＤＳ）患者治疗前后其体内肿瘤坏死因子（ＴＮＦ）活性变化。结果显示ＭＤＳ患者血清ＴＮＦ活性（５．９０±４．７６ｕ／ｍｌ）较正常人明显减低（１３．８７±７．５９ｕ／ｍｌ）（Ｐ＜０．０５），治疗后ＭＤＳ患者血清ＴＮＦ活性为９．３６±５．０７ｕ／ｍｌ，与治疗前比较差异显著（Ｐ＜０．０５）。研究结果还显示：在ＭＤＳ各亚型中，ＲＡ治疗后血清ＴＮＦ活性恢复明显高于ＲＡＥＢ和ＲＡＥＢ－Ｔ，提示ＴＮＦ活性变化对ＭＤＳ的病情变化及预后判断有重要临床意义。
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| 关 键 词： | 肿瘤坏死因子，骨髓增生异常综合征，预后 |
Relationship Between Activity of TNF and Prognosis in Patients with Myelodysplastic Syndrome |
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| Zhu Yan,et al.Relationship Between Activity of TNF and Prognosis in Patients with Myelodysplastic Syndrome[J].Journal of Jiangsu University Medicine Edition,1996(4). |
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| Authors: | Zhu Yan |
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| Institution: | Affiliated Hospital of Zhenjiang Medical College |
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| Abstract: | |
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| Keywords: | Tumor necrosis factor Myelodysplastic syndrome Prognosis |
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