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| 槟榔碱与银杏外种皮提取物联合用药杀灭钉螺的研究 | |
| 引用本文： | 陈盛霞,杨小明,张蓉仙,李龙根,吴亮,邵世和.槟榔碱与银杏外种皮提取物联合用药杀灭钉螺的研究[J].江苏大学学报(医学版),2007,17(1):1-4. |
| 作者姓名： | 陈盛霞 杨小明 张蓉仙 李龙根 吴亮 邵世和 |
| 作者单位： | 1. 江苏大学医学技术学院,江苏,镇江,212003 2. 江苏大学化学化工学院,江苏,镇江,212013 3. 江苏大学镇江市疾病预防控制中心,江苏,镇江,212003 |
| 摘 要： | 目的:探讨槟榔碱与银杏外种皮提取物联合用药实验室浸杀钉螺的效果.方法:将经石油醚、乙酸乙酯和无水乙醇提取的银杏外种皮提取物稀释成不同浓度,用浸杀法观察24,48,72,96 h的杀螺效果;并与槟榔碱水提物联合用药的杀螺效果进行比较.结果:银杏外种皮石油醚、乙酸乙酯和无水乙醇提取物杀灭钉螺的LC50分别为7.81,27.33和64.14 mg/L,LC90分别为32.70,54.94和170.07 mg/L;与槟榔联合用药后其LC50分别降低为0.85,2.10和10.80 mg/L,LC90分别降低为2.55,5.93和29.97 mg/L.结论:银杏外种皮提取物对钉螺有较好的杀灭作用,槟榔碱的使用可明显降低银杏外种皮提取物的用量. |
| 关 键 词： | 钉螺 银杏 外种皮 槟榔碱 槟榔碱 银杏外种皮提取物 联合用药 杀灭钉螺 研究 arecoline combined Ginkgo biloba extracts effects 用量 使用 杀灭作用 乙醇提取物 结果 比较 水提物 杀螺效果 浓度 稀释 |
| 文章编号： | 1671-7783（2007）01-0001-04 |
| 收稿时间： | 2006-10-08 |
| 修稿时间： | 2006年10月8日 |
Study on molluscidal effects of extracts from sarcotesta of Ginkgo biloba combined with arecoline |
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| CHEN Sheng-xia,YANG Xiao-ming,ZHANG Rong-xian,LI Long-gen,WU Liang,SHAO Shi-he.Study on molluscidal effects of extracts from sarcotesta of Ginkgo biloba combined with arecoline[J].Journal of Jiangsu University Medicine Edition,2007,17(1):1-4. | |
| Authors: | CHEN Sheng-xia YANG Xiao-ming ZHANG Rong-xian LI Long-gen WU Liang SHAO Shi-he |
| Institution: | 1. School of Medical Technology; 2. School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang Jiangsu 212013 ; 3. Zhenjiang Center for Disease Control and Prevention, Zhenjiang Jiangsu 212003 ,China |
| Abstract: | Objective: To study molluscidal effects of extracts from sarcotesta of Ginkgo biloba combined with arecoline.Methods: Oncomelania hupensis was immersed in different concentrations of extracts from Sarcotesta of Ginkgo biloba by benzinum,acetic ether or absolute alcohol.Molluscidal effects were observed at 24,48,72,96 h,and compared with those of extracts from sarcotesta of Ginkgo biloba combined with arecoline. Results: At 24 h the LC50 were 7.81,27.33 and 64.14 mg/L,respectively,LC90 were 32.70,54.94 and 170.07 mg/L,respectively.The LC50,combined with arecoline,were declined to 0.85,2.10 and 10.80 mg/L,respectively,LC90 were declined to 2.55,5.93 and 29.97 mg/L,respectively. Conclusion: The extracts from sarcotesta of Ginkgo biloba possessed molluscidal effects.The dose of the extracts could reduce markedly when used with arecoline. |
| Keywords: | Oncomelania hupensis Ginkgo biloba sarcotesta Arecoline |
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