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长春瑞滨联合阿霉素和顺铂治疗乳腺癌肺转移临床观察
引用本文:杜宏斌,钱建新.长春瑞滨联合阿霉素和顺铂治疗乳腺癌肺转移临床观察[J].安徽医学,2006,27(3):207-208.
作者姓名:杜宏斌  钱建新
作者单位:1. 234000,宿州市中煤三建总医院肿瘤内科
2. 上海市第二军医大学附属长征医院肿瘤科
摘    要:目的观察长春瑞滨(NVB)联合阿霉素(ADM)和顺铂(DDP)治疗乳腺癌肺转移的临床疗效。方法24例乳腺癌肺转移采用NVB25mg/m2d1、8+ADM40mg/m2d1+DDP25mg/m2d1~3方案联合化疗。结果CR4例,PR13例,总有效率(CR+PR)71%。主要毒副反应为骨髓抑制和静脉炎,采用深静脉置管给药可减少静脉炎发生。结论NAP方案治疗乳腺癌肺转移疗效较高。

关 键 词:乳腺癌肺转移/药物疗法  药物疗法  联合  长春瑞滨/治疗应用
收稿时间:2005-10-17
修稿时间:2005-10-172006-03-10

The Cilinical Observation of NVB Combined with Adriamycin and Cisplatin in Breast Cancer with Lung Metastases
Du Hongbin,Qian Jianxin.The Cilinical Observation of NVB Combined with Adriamycin and Cisplatin in Breast Cancer with Lung Metastases[J].Anhui Medical Journal,2006,27(3):207-208.
Authors:Du Hongbin  Qian Jianxin
Institution:General Hospital of China Coal Mine the Third Construction Suzhou Anhui 234000 ;The Changzheng Hospital affiliated to the second military medical university Shanghai 200070
Abstract:To observe the clinical effect of NVB combined ADM and cisplatin in breast cancer with lung metastases.24 caces were treated by regimen of NVB 25 mg/m2 d_ 1、8 +ADM 40 mg/m2 d_1+DDP 25 mg/m2 d_ 1~3 .the result showed CR was 4 cases,PR was 13 cases,overall response rate (CR+PR) was 71%.The main adverse effects were bone marrow depression and phlebitis.Cavity in deep venous could avoid the effect.NAP regimen is effective in treating breast cancer with lung metastasis.
Keywords:Breast cancer with lung metastasis/drug treatment  Drug treatment  Combination  NVB/therapeutic effect
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