铜陵市住院脑血管病患者慢性肾脏病流行病学调查

目的研究铜陵住院脑血管病患者慢性肾脏病(CKD)患病率及相关危险因素。方法收集铜陵市人民医院神经内科2010年5月至2011年10月间住院脑血管病患者临床资料,所有患者均经脑及脑血管CT、脑及脑血管MRI确诊,进行CKD及相关危险因素检测和问卷调查。结果共获得1 488例完整资料,蛋白尿、eGFR下降及血尿患病率分别为9.88%、4.03%以及2.08%。该人群CKD患病率为14.31%,知晓率为9.4%。女性、年龄、糖尿病、高血压和高尿酸血症是CKD的独立危险因素,高胆固醇和高三酰甘油与CKD发病率增高无关。结论铜陵住院脑血管病患者CKD患病率为14.31%,知晓率为9.4%。女性、年龄、高血压、糖尿病及高尿酸血症是CKD的独立危险因素。

Epidemiologic study of chronic kidney disease from inpatients with cerebrovascular diseases in Tongling

Objective To explore the prevalence,awareness and risk factors of chronic kidney diseases(CKD) of inpatients with cerebrovascular diseases in Tongling district.Methods Inpatients with cerebrovascular diseases from neurology department of Tongling People’s Hospital from May.2010 to Oct.2011 were recruited.All the inpatients were respectively diagnosed by brain CT,CTA,MRI and MRA and they were interviewed and tested for urinary albumin to creatinine ratio(abnormal:≥,30mg/g) and hematuria(microscopic examination of centrifuged urine sediment).Estimated glomerular filtration rate(eGFR) were calculated with the simplified MDRD equation modified by a Chinese coefficient.The risk factors associated with CKD were also investigated.Results Total 1488 hospitalized patients with cerebrovascular diseases were enrolled during the observation period.Albuminuria was detected in 9.88% of subjects,reduced eGFR in 4.03% and hematuria in 2.08%.Approximately 14.31% subjects had at least one indicator of kidney damage.The awareness rate of CKD was 9.4%.Female,age,hypertension,diabetes mellitus and hyperuricaemia were independently associated with CKD,while hypercholesteremia and hypertriglyceridemia were not associated with the prevalence of CKD.Conclusion The prevalence of chronic kidney disease is 14.31% and the awareness rate is 9.4% of inpatients with cerebrovascular diseases in Tongling district.Independent risk factors associated with CKD are female,age,hypertension,diabetes mellitus and hyperuricaemia.