| S100 PROTEIN-POSITIVE DENDRITIC CELLS AND THE SIGNIFICANCE OF THEIR DENSITY IN GASTRIC PRECANCEROUS LESIONS |
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| 作者姓名： | 黄建 黄怀德 彭清璧 朱志建 余心如 |
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| 作者单位： | Zhejiang Branch CAMS，Hanozhou，Zhejiang Branch，CAMS，Hanozhou，Zhejiang Branch，CAMS，Hanozhou，Zhejiang Branch，CAMS，Hanozhou，Zhejiang Branch，CAMS，Hanozhou |
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| 摘 要： | Quantitative analysis of dendritic cells (DC's) was carried out in tissue specimens of normalgastric mucosa (n=15),gastric ulcer (n=19),chronic atrophic gastritis (n=28),and gastriccarcinoma (n=65) by ABC immunostaining with S100 protein antibody.Significant increasein DC number were observed in chronic atrophic gastritis with type Ⅲ intestinal metaplasiaand/or grade Ⅱ,Ⅲ dysplasia.The result suggests that DC's are potentially capable opresenting neoantigens associated with malignant transformation at the precancerous stagewhen malignant morphological changes have not yet taken place.Combined with routinediagnostic methods,the serial monitoring of DC density in gastric mucosa may be usefulin the follow-up of premalignant lesions in the stomach and the diagnosis of early gastriccarcinoma.
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S100 PROTEIN-POSITIVE DENDRITIC CELLS AND THE SIGNIFICANCE OF THEIR DENSITY IN GASTRIC PRECANCEROUS LESIONS |
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| Huang Jian Huang Huaide Peng Qingbi Zhu Zhijian Yu Xinru Zhejiang Branch,CAMS,Hanozhou.S100 PROTEIN-POSITIVE DENDRITIC CELLS AND THE SIGNIFICANCE OF THEIR DENSITY IN GASTRIC PRECANCEROUS LESIONS[J].Chinese Medical Sciences Journal,1990(2). |
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| Authors: | Huang Jian Huang Huaide Peng Qingbi Zhu Zhijian Yu Xinru Zhejiang Branch CAMS Hanozhou |
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| Abstract: | |
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| Keywords: | S100 protein dendritic cell stomach precancerous lesion |
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