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壮筋膏的抗炎镇痛作用研究
引用本文:彭锐,邹阳.壮筋膏的抗炎镇痛作用研究[J].湖北中医学院学报,2007,9(1):17-18.
作者姓名:彭锐  邹阳
作者单位:湖北中医学院针灸骨伤系骨伤教研室 湖北武汉430061(彭锐),湖北省中医药研究院 湖北武汉430074(邹阳)
基金项目:湖北省自然科学基金项目,[2002AB118]
摘    要:目的通过对壮筋膏的药效学研究,评价壮筋膏的抗炎镇痛作用。方法采用小鼠耳廓二甲苯致炎试验、大鼠蛋清足跖肿胀试验进行抗炎作用研究;采用小鼠热板法、小鼠醋酸扭体法进行镇痛作用研究。结果壮筋膏有明显抑制炎症模型小鼠耳廓肿胀和足趾肿胀的作用,能延长热痛试验中小鼠舐后足的时间,能明显减少醋酸所致小鼠扭体的次数。其作用呈一定的量效关系。结论壮筋膏具有明显的抗炎、镇痛作用。

关 键 词:壮筋膏  中药  抗炎镇痛  实验研究
文章编号:24054168
修稿时间:06 10 2006 12:00AM

Study of Zhuangjin Ointment on Suppressing Inflammation and Alleviating Pains
PENG Rui,ZOU Yang.Study of Zhuangjin Ointment on Suppressing Inflammation and Alleviating Pains[J].Journal of Hubei College of Traditional Chinese Medicine,2007,9(1):17-18.
Authors:PENG Rui  ZOU Yang
Institution:1. Hubei College of Traditional Chinese Medicine,Wuhan 430061; 2.Hubei Academy of Traditional Chinese Medicine and Pharmacy, Wuhan 430074
Abstract:Objective: To evaluate the effect on suppressing inflammation and alleviating pains of Zhuangjin Ointment.Methods: The mice's auricular swelling test,the rat's toe swelling test caused by albumen,the mice's pain-test by hot and the mice's wrenching body test caused by the irritation of acetic acid were conducted.Results:Zhuangjin Ointment could depress swelling of the mice in auricular swelling test,inhibit the rat's toe swelling caused by albumen,prolong the time of the mice's lapping back legs during the pain-test by hot and could reduce the times of wrenching their bodies caused by the irritation of acetic acid sharply.Conclusion: Zhuangjin Ointment has the effects of suppressing inflammation and alleviating pains.
Keywords:Zhuangjin Ointment  Traditional Chinese medicine  Experiment of suppressing inflammation and alleviating pains
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