| 18例慢性再生障碍性贫血骨髓造血细胞与微环境超微结构的动态研究 |
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| 引用本文： | 张圣明,李建华,崔为发,白林,刘荣卿,王树庆,薛吉年,冯增立.18例慢性再生障碍性贫血骨髓造血细胞与微环境超微结构的动态研究[J].潍坊医学院学报,1989(4). |
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| 作者姓名： | 张圣明 李建华 崔为发 白林 刘荣卿 王树庆 薛吉年 冯增立 |
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| 作者单位： | 潍坊医学院组胚教研室，潍坊医学院中医科教研室，潍坊医学院内科学教研室，潍坊医学院组胚教研室，潍坊医学院中医科教研室，潍坊医学院中医科教研室，中国科学院生物物理所，中国科学院生物物理所 |
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| 摘 要： | 对18例CAA患者与5例正常人的骨髓用透射电镜进行了研究。缓解后观察12例,其中9例是治疗前后的自身动态观察。发现所有患者的造血细胞与基质细胞与正常人相比均有不同程度的双重病变。治疗后随缓解程度又有不同的双重恢复,基质细胞恢复优于造血细胞。所有细胞器恢复最早的是线粒体和细胞膜,其后是细胞核。研究结果对CAA的发病机理和病理生理做出了较好的解释。
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| 关 键 词： | 贫血 再生障碍性 骨髓 透射电镜 动态研究 |
DYNAMIC STUDY OF HEMOTOCYTE AND HEMOPOIETIC MICROENVI RONMENT IN BONE MARROW OF 18 CASES CHRONIC APLASTIC A(?)EMIA |
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| Zhang Shengming,et al.DYNAMIC STUDY OF HEMOTOCYTE AND HEMOPOIETIC MICROENVI RONMENT IN BONE MARROW OF 18 CASES CHRONIC APLASTIC A(?)EMIA[J].Journal of Weifang Medical College,1989(4). |
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| Authors: | Zhang Shengming |
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| Institution: | Weifang Medical College |
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| Abstract: | 18 cases with chronic aplastic anemia and 5 normal persons of bone marrow were studied by transmission electron mic(?)oscope. 12 cases of remission were observed, 9 patients of them were studied by selfactive observation before and after treatment. We found that certain double pathologic changes were occurred to the hemotocytes and stromatic cells of all patients. Pathologic changes has certain recovery after treatment, the stromatic cells superior to the hemotocytes Mitochondrions and membrane of cells are the earliest among all the recovering organs of all cells, and the nucleus is the last one. Our stu(?)y result explained betterly about pathogenesis and pathological physiology suffering from CAA. |
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| Keywords: | anemia aplastic bone marrow transmission electran microscope dynamic study |
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