| 丹皮酚对大鼠脑内单胺神经递质的影响 |
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| 引用本文： | 陈维宁,谢林.丹皮酚对大鼠脑内单胺神经递质的影响[J].潍坊医学院学报,1995,17(1):20-22. |
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| 作者姓名： | 陈维宁 谢林 |
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| 作者单位： | 中国药科大学药理学教研室 |
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| 摘 要： | 用高效液相色谱－电化学器方法，研究了丹皮酚对大鼠脑内单胺神经递质代谢的影响。结果表明，丹皮酚能增加大鼠纹状体及边缘内多巴胺代谢物高香草酸和三羟苯乙酸含量，也以增加５－羟色胺代谢物５－羟吲哚醋酸的含量，对单胺递质ＮＡ及ＤＡ含量无明显影响。
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| 关 键 词： | 丹皮酚 单胺递质 二羟苯乙醇 高效液相色谱 |
EFFECT OF PAEONOL ON MONOAMINE TRANSMITTER METABOLISM IN RAT BRAIN |
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| Chen Weining,Liu Xuejun ,Dai Gong.EFFECT OF PAEONOL ON MONOAMINE TRANSMITTER METABOLISM IN RAT BRAIN[J].Journal of Weifang Medical College,1995,17(1):20-22. |
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| Authors: | Chen Weining Liu Xuejun Dai Gong |
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| Abstract: | This paper reported the effect of paeonol on monoamine metabolism in rat brain.This experiment was carried out with HPIC-electrochemical detector,The results showed that the levels of homovanillic acid(HVA) and dihydroxphenylacetic acid (DOPAC) in striatum and limbic areas increased after 40 minutes ip of paeonol 100mg/kg in rat.Increase in 5-hydroxyindoleacetic acid(5-HIAA)levels of in the striatum and limbic areas was also abserved.But the levels of monoamine transmitters nora-trenaline (NA) and DA remained unchange. |
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| Keywords: | paeonol monoamine transmitter dihydroxyphenylacetic acid homovanillic acid high performance liquid chromatography |
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