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白细胞介素-2对慢性乙型肝炎干扰素诱生的影响
引用本文:李熙芹,陈白玉,杨赟.白细胞介素-2对慢性乙型肝炎干扰素诱生的影响[J].湘南学院学报(医学版),2001(3).
作者姓名:李熙芹  陈白玉  杨赟
作者单位:郴州医专免疫学与微生物学教研室,郴州医专附属医院,郴州医专免疫学与微生物学教研室 湖南郴州423000
摘    要:目的 为探讨白细胞介素 - 2 (IL - 2 )对慢性乙型肝炎 (CHB)患者干扰素 (IFN)诱生的影响。方法 应用IL - 2 2万单位静脉滴注治疗CHB ,治疗前后测定肝功能、HBV -M和IFN。结果 实验组IFN定量 >30pg ml 16例 (6 9.5 % ) ,对照 2例 (8.7% ) ,两组差异显著 (x2 =17.9,p <0 .0 1)。结论 IL - 2能诱导CHB产生干扰素

关 键 词:白细胞介素-2  慢性乙型肝炎  干扰素

Effects of Jnterleukin 2 on the Induced Formation of Interferon in Patients with Chrouic Hepatitis B
Li Xiqin,Chen Baiyu,Yang Yun.Effects of Jnterleukin 2 on the Induced Formation of Interferon in Patients with Chrouic Hepatitis B[J].JOurnal of Xiangnan University:Medical Sciences,2001(3).
Authors:Li Xiqin  Chen Baiyu  Yang Yun
Abstract:Objective To investigate the effects of interleukin2(IL-2)on the induced formation of interferon (IFN) in chronic hepatitis B(CHB).Methods U intravenous drip of 20,000 IL-2 was taken to treatCHB. The liver function, HBV-Mand IFN were examinated around treatment.Results There were 16 cases that IFN quotas was more than 30pg/ml (69.5%) in the experimental group, but only two cases (8.7%) in control group, there were significantly differences between the two groups (x 2=17.9,9<0.01).Conclusion IL-2 can induce CHB to form interfenon.
Keywords:Interleukin 2  Chronic hepatitis B  Interferon  Quota
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