针灸对原发性骨质疏松症影响的实验研究

采用１２月龄雌性ＳＤ大鼠６５只，随机分为正常对照组、假手术组、模型一醇组、针刺组和艾灸组，切除双侧卵巢法建立骨质疏松模型，造模３个月后治疗３个月，骨代谢生化指标、性激和学等观察针刺和艾灸治疗原发性骨质疏松症的疗效。结果：经针刺、艾灸或雌二醇治疗后，血清Ｃａ无明显变化（Ｐ〉０．０５），血清ＡＫＰ较模型组分别有所下降（Ｐ〈０．０５）；血清Ｅ２、ＢＧＰ、ＰＴＨ较模型组升高（Ｐ〈０．０５～０．０１），股骨

Experimental Study on Effect of Acupuncture & Moxibustion to Primary Osteoporosis

female rat of 12 months were divided at radom into 6 groups,such as normal control,pseudo operation,model,estradiol,acupuncture and moxibustion. The method of spay was used for establishing the model of osteoporosis. A3 months course of treatment was carried out 3 months after operation. The biochemical indexes of bone metabolism,sexual hormones level and biomechanics indexes were used for the observation of the effect. The result showed that,after the treatment of acupuncture,moxibustion or estradiol,the level of serum Ca changed unobviously(P>0.05).Compared with that in model group,the serum AKP reduced (P<0.05) ,while the serum E 2, BGP and PTH rised (P<0.05~0.01).The elastic modulus,the yield point energy and the destructive enery of femur changed obviously (P<0.01),compared with those in model group. It can be concluded as that the effect of acupuncture moxibustion and estradiol show no difference. The therapy of acupuncture and moxibustion is one of the effective methods for the prevention and treatment of osteoporosis.