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Effects of Ge Gen Decoction on PGE2 Content and COX Activity in the Degenarated Cervical Intervertebral Discs of Rats
作者姓名:周军  方素萍  霍海如  齐云  郭淑英  姜廷良  施杞  王友京
作者单位:[1]Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China [2]Department of Molecular Biology, Guang'anmen Hospital, Beijing [3]Institute of Orthopedics & Traumatology, Shanghai University of TCM [4]不详, Shanghai University of TCM
摘    要:

关 键 词:葛根  PGE2  环氧合酶  酶活性  子宫疾病  中医药疗法

Effects of Ge Gen Decoction on PGE2 Content and COX Activity in the Degenarated Cervical Intervertebral Discs of Rats
Zhou Jun,Fang Suping,Huo Hairu,Qi Yun,Guo Shuying,Jiang Tingliang,Shi Qi,Wang Youjing.Effects of Ge Gen Decoction on PGE2 Content and COX Activity in the Degenarated Cervical Intervertebral Discs of Rats[J].Journal of Traditional Chinese Medicine,2005,25(3):222-225.
Authors:Zhou Jun  Fang Suping  Huo Hairu  Qi Yun  Guo Shuying  Jiang Tingliang  Shi Qi  Wang Youjing
Institution:Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Abstract:After the rat model of cervical spondylosis was developed for 6 months, the PGE2 content and COX activity in the cervical intervertebral discs were determined respectively by radioimmunoassay and catalytic activity assay.The results indicated that the PGF2 content and COX activity in the model rat increased significantly, and that Ge Gen Decoction could down-regulate the PGE2 content and inhibit COX activity. This is possibly one of the mechanisms of Ge Gen Decoction for treating cervical spondylosis.
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