Effects of Electroacupuncture on Hippocampal and Cortical Apoptosis in A Mouse Model of Cerebral Ischemia-reperfusion Injury |
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Authors: | ZHAO Jian-xin TIAN Yuan-xiang XIAO Hong-ling HU Man-xiang CHEN Wei-ran |
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Institution: | ZHAO Jian-xin 1,TIAN Yuan-xiang 2,XIAO Hong-ling 3,HU Man-xiang 4,and CHEN Wei-ran 3 1. The Third Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100029,China,2.Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,3.Traditional Chinese Medical College of Hebei Medical University,Shijiazhuang 050091,Hebei,4.Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang 050051 |
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Abstract: | Objective: To observe the effects of electroacupuncture on hippocampal and cortical apoptosis in a mouse model of cerebral ischemia-reperfusion injury. Methods: Mouse models established by repeated cerebral ischemia-reperfusion, followed by electroacupuncture at Shenshu, Geshu, and Baihui points. The control group mice were intragastrically administered Hydergine. On day 1 and 7 post-treatment, hippocampal and cortical apoptosis was detected by terminal-deoxynucleotidyl transferase mediated dUTP nick-end la... |
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Keywords: | electroacupuncture cerebral ischemia-reperfusion hippocampus cortex neurons apoptosis image analysis |
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