亚急性坏死性淋巴结炎30例临床分析

目的 探讨亚急性坏死性淋巴结炎（subacute necrotizing lymphadenitis,SNL）的病因及临床特征，分析相关实验室检查项目特点，提高对SNL的认识及与其他疾病的鉴别。方法 结合文献资料回顾分析30例临床病例。结果 临床特征表现发热、淋巴结肿大、白细胞减少；抗EB病毒抗体阳性率高；淋巴结活检确诊。结论 对于临床年轻患者不明原因发热伴淋巴结肿大疼痛者，可检查白细胞及抗EBV抗体，进而行淋巴结活检确诊，病程呈自限性，或结合糖皮质激素治疗。

Clinical Analysis of Subacute Necrotizing Lymphadenitis 30 Cases with Literature Review

Objective To investigate etiological factors,clinical characteristic and related laboratory findings of subacute necrotizing lymphadenitis(SNL),to improve the acknowledgement level of SNL diagnosis and differential diagnosis Method Analyzing 30 cases of SNL and reviewing the related literature Result Clinical presentation of SNL includes fever,lymphadenopathy and leucocytopenia Serum antibody of EB virus was positive in many cases Diagnosis of SNL should be finally confirmed by lymph node biopsy Conclusion SNL should be considered when a young patient with fever of unknown origin,swelling and painful lymph nodes While routine blood analysis and assay of EB virus antibody are usually required,the lymph node biopsy is the only way to make SNL diagnosis The process of SNL is self-limited disorder,can also be cured with glucocorticoids