| 慢性阻塞性肺疾病与骨质疏松症病因的探讨 |
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| 引用本文： | 王红武,吴剑芸.慢性阻塞性肺疾病与骨质疏松症病因的探讨[J].广州医学院学报,2003,31(2):50-51,57. |
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| 作者姓名： | 王红武 吴剑芸 |
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| 作者单位： | 广州医学院附属市一医院老年病科,广东,广州,510180 |
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| 摘 要： | 目的:通过观察慢性阻塞性肺疾病(COPD)患者骨密度(BMD)的变化,分析其与骨质疏松症的关系。方法:测定76例慢性阻塞性肺疾病患者及对照组59例的肺功能、血气、腰椎和股骨近端部位的骨密度以及血钙、磷等生化指标。结果:慢性阻塞性肺疾病组较对照组的L1、L3、Ward's三角、股骨颈的骨密度明显降低(P<0.01);且慢性阻塞性肺疾病组骨质疏松发生率较高(P<0.01),慢性阻塞性肺疾病组骨密度与氧分压有一定的相关性(P<0.05)。结论:慢性阻塞性肺疾病患者较易发生骨质疏松,低氧血症可能是一重要原因。
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| 关 键 词： | 肺疾病 骨质疏松 低氧血症 |
| 文章编号： | 1008-1836(2003)02-0050-02 |
The Clinical Relationship between Chronic Obstructive Pulmonary Diseases and Osteoporosis |
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| WANG Hong-wu,WU Jian-yun.The Clinical Relationship between Chronic Obstructive Pulmonary Diseases and Osteoporosis[J].Academic Journal of Guangzhou Medical College,2003,31(2):50-51,57. |
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| Authors: | WANG Hong-wu WU Jian-yun |
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| Abstract: | Objective:To analyse the data on bone mineral density( BMD) in COPD for an exploration of its association with osteoporosis. Methods: pulmonary function,blood gas analysis,BMD of lumbar vertebrae and proximal femur, blood Ca2+ and P3- levels in 76 COPD patients and 59 controls were measured. Results: In COPD group the BMD data of L1 , L3, Ward's trigone and femoral neck were significantly decreased ( P < 0. 01 , P < 0. 01 ) and the prevalence of osteoporosis was relatively higher as compared with those in control group. BMD data showed correlation with PaO2 in patients with COPD (F <0.05). Conclusion: Patients with COPD are prone to develop osteoporosis,where hypoxemia may be one among precipitating factors. |
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| Keywords: | COPD osteoporosis |
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