| 血清血管紧张素转化酶测定及其在肺部疾病的初步应用 |
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| 引用本文： | 王正中,范家凌,唐文淦.血清血管紧张素转化酶测定及其在肺部疾病的初步应用[J].重庆医科大学学报,1985(1). |
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| 作者姓名： | 王正中 范家凌 唐文淦 |
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| 作者单位： | 重庆医学院第一医院肺科
(王正中)，重庆医学院中心实验室
(范家凌)，重庆医学院中心实验室(唐文淦) |
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| 摘 要： | 本文报告使用国产马尿酰甘氨酰甘氨酸为底物,以紫外分光光度计测定血清血管紧张素转化酶(SACE)的方法。并对69例正常人、55例肺结核、46例肺癌、4例淋巴瘤、3例肺炎及1例临床疑诊为结节病患者进行了SACE测定:结果:正常值35.38±8.7u(X±SD);肺结核、肺癌患者的SACE与正常人无显著差异;1例疑诊为结节病者显著增高(69.45u)。认为SACE测定可作为结节病辅助诊断检测项目之一;对非结节病性肺部疾病的SACE活性变化,有待进一步观测、研究。
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| 关 键 词： | 血清血管紧张素转化酶 马尿酰甘氨酰甘氨酸 紫外分光光度计 |
MEASUREMENT OF SERUM ANGIOTENSIN CONVERTING ENZYME IN PULMONARY DISEASES AND ITS PRELIMINARY APPLICATION |
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| Institution: | Department of Pulmonary Medicine:Wang Zhengzhong,Department of Central Laboratory: Tang wengan,Fan Jialing |
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| Abstract: | Serum angiotensin converting enzyme (SACE) activity was determined with hippuryl-glycyl-glycine (HGG) as substrate in 69 healthy adults, 55 cases of pulmonary tuberculosis, 46 cases of lung cancer, 4 cases of lymphoma,3 cases of pneumonia and 1 case suspicious of sarcoidosis. The level of SACE in healthy adults was 35.38+8.7u (mean +SD).The difference of the level of SACE between pulmonary tuberculosis and cancer patients and healthy adults was not statistically significant. But the level of SACE activity in 1 suspected sarcoidosis was 69.45u, much higher than that of the healthy adult.We suggest that measurement of SACE activity may be taken an aid in the diagnosis of active sarcoidosis. But for pulmonary diseases other than sarcoidosis evaluation of the test awaits further study. |
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| Keywords: | Serum angiotensin converting enzyme (SACK) hippuryl-glycyl-glycine (HGG) ultraviolet Spectrophotometer |
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