| 睡眠剥夺后静息状态下前扣带回功能连接模式的改变 |
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| 引用本文： | 叶恩茂,邵永聪,毕国华,马林,杨征,陈武凡. 睡眠剥夺后静息状态下前扣带回功能连接模式的改变[J]. 医学争鸣, 2009, 0(19): 2002-2004 |
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| 作者姓名： | 叶恩茂 邵永聪 毕国华 马林 杨征 陈武凡 |
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| 作者单位： | 南方医科大学生物医学工程学院;军事医学科学院基础医学研究所;第四军医大学航空航天医学系心理学教研室;解放军总医院; |
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| 摘 要： | 目的：探讨睡眠剥夺对静息态脑功能连接模式的影响.方法：对14名健康男性大学生进行两次静息态功能磁共振成像扫描.第1次扫描在正常睡眠清醒后12h完成,第2次扫描于睡眠剥夺36h后完成.选取前扣带回为种子区域进行静息态脑功能连接分析.结果：睡眠剥夺后与前扣带回的功能连接增强的脑区有顶叶皮层、岛叶、颞叶等,下降的脑区有丘脑.结论：清醒状态的维持主要由丘脑等皮层下区域负责,机体的默认网络系统在睡眠剥夺后功能连接增强,反映了默认网络系统功能的一致变化,这与机体的注意、抑制功能的下降及清醒状态的下降相关.
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| 关 键 词： | 睡眠剥夺 功能磁共振成像 前扣带回 功能连接 默认网络 |
Changes of functional connectivity of ACC in resting state during sleep deprivation:An fMRI study |
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| YE En-Mao,SHAO Yong-Cong,BI Guo-Hua,MA Lin,YANG Zheng,CHEN Wu-FanBiomedical Medical Engineering Institute,Southern Medical University,Guangzhou ,Beijing Institute of Basic Medical Sciences,Beijing . Changes of functional connectivity of ACC in resting state during sleep deprivation:An fMRI study[J]. Negative, 2009, 0(19): 2002-2004 |
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| Authors: | YE En-Mao SHAO Yong-Cong BI Guo-Hua MA Lin YANG Zheng CHEN Wu-FanBiomedical Medical Engineering Institute Southern Medical University Guangzhou Beijing Institute of Basic Medical Sciences Beijing |
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| Affiliation: | YE En-Mao1,2,SHAO Yong-Cong2,3,BI Guo-Hua2,MA Lin4,YANG Zheng2,CHEN Wu-Fan11Biomedical Medical Engineering Institute,Southern Medical University,Guangzhou 510515,2Beijing Institute of Basic Medical Sciences,Beijing 100850,3Department of Aerospace Psychology,Fourth Military Medical University,Xi'an 710033,4General Hospital of People's Liberation Army of China,Beijing 100083,China |
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| Abstract: | AIM:To explore the impact of total sleep deprivation(TSD)on functional connectivity of ACC in resting state.METHODS:Healthy young men(n=14)completed rest fMRI scan before and after the 36-TSD.fMRI scans were carried out in these subjects 3 weeks apart.RESULTS:TSD induced positive and negative functional connectivity compared with that after the normal sleep.The activated areas with positive FC include the PC,etc.and with negative FC in thalamus.CONCLUSION:The maintaining of awareness is supported by thalamu... |
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| Keywords: | total sleep deprivation functional magnetic resonance imaging anterior cingulated cortex functional connectivity |
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