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医用TH胶栓塞血管后组织学改变的实验观察
引用本文:晋援朝,丁华野.医用TH胶栓塞血管后组织学改变的实验观察[J].第四军医大学学报,1994,15(5):360-363.
作者姓名:晋援朝  丁华野
作者单位:西京医院血管外科,病理学教研室
摘    要:作对医用TH胶血管栓塞后组织学的变化及栓塞剂在血管内的远期归宿进行了动物实验,并观察3年,资料表明,TH胶在血管内以机械堵塞方式使血流中断,该段血管表现为血栓性静脉炎的病理过程,由于TH胶在聚合时产热和它的不吸收性,对血管产生的机械性损伤和化学性刺激,使血管壁破坏,随着时间的延长,纤维组织增生并突入管腔,逐渐将TH胶分隔代替,管腔机化,说明TH胶对血管的栓塞是不易再腔化的永久性栓塞,它的栓塞止血

关 键 词:TH胶  栓塞剂  血管栓塞术  组织学

The vascular histological changes after vascular embolization withmedical TH tissue adhesive in experimental animals
JIN Yuan-Chao,YANG Zhen- Dong,YAO Xiao- Xian,DING Hua- Yie,ZHU Ming-HuaandMAFu- Cheng.The vascular histological changes after vascular embolization withmedical TH tissue adhesive in experimental animals[J].Journal of the Fourth Military Medical University,1994,15(5):360-363.
Authors:JIN Yuan-Chao  YANG Zhen- Dong  YAO Xiao- Xian  DING Hua- Yie  ZHU Ming-HuaandMAFu- Cheng
Institution:JIN Yuan-Chao1,YANG Zhen- Dong1,YAO Xiao- Xian1,DING Hua- Yie2,ZHU Ming-Hua2andMAFu- Cheng2 1 Department of VascularSurgery,Xi jing Hospital 2Department of Pathology
Abstract:The vascular histological changes following vascular embolization with medical TH tissue adhesiveand the long- time endovascular effect of this embolic agent were studied in animal experiment.Results showed that the TH tissue adhesiveblockedbloodflowbymechanicalobstruction. Theblockedbloodvesselsmenifested embolic vasculitis-like pathological process.Being unabsorbed , TH tissue adhesive destroyed vas-cular wall by mechanical injury and chemical stimulation. The blocked blood vessels were eventually replaced by fibrotissues.This suggested that the vascular embolization with TH tissue adhesive is permanent and could not be easily recanalized.Its hemostatic effect is permanent and reliable.
Keywords:TH tissue adhesive  embolic agent  vascular embolization
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