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超声检测颈动脉粥样硬化及其与冠心病的相关性分析
引用本文:沈敏,李兰荪,贾国良,郭文怡,王海昌.超声检测颈动脉粥样硬化及其与冠心病的相关性分析[J].第四军医大学学报,2003,24(6):532-535.
作者姓名:沈敏  李兰荪  贾国良  郭文怡  王海昌
作者单位:第四军医大学西京医院心血管内科,陕西,西安,710033
摘    要:目的:通过对颈动脉内中膜厚度(IMT)及颈动脉粥样硬化斑块的检测,探讨颈动脉粥样硬化病变的发生与冠心病的关系及其与冠心病危险因素的关系。方法:应用高频超声测定IMT及斑块的超声分级,并与冠心病的多种危险因素进行分析。检测的90例患中,经冠脉造影证实,冠心病组69例,对照组21例。结果:冠心病组中,IMT明显大于对照组,但冠脉病变组之间无差异。冠心病组的颈动脉硬化斑块的检出率明显高于对照组,且与冠脉病变的严重程度有关,以分叉部为最高,依次为颈总动脉和颈内动脉,总胆固醇(TC),低密度脂蛋白胆固醇(LDL-C)水平及高血压,糖尿病发病率在冠心病组中明显高于对照组。结论:颈动脉粥样硬化严重程度与冠心病发病率成正比。颈动脉超声可对冠心病的多种危险因素进行预测。

关 键 词:颈动脉  动脉粥样硬化  冠状动脉疾病  超声检查  危险因素
文章编号:1000-2790(2003)06-0532-04
修稿时间:2002年6月5日

Relationship between carotid atherosclerosis and coronary artery disease
Abstract:AIM: To evaluate the relationship between carotid atherosclerosis and coronary artery disease (CAD) by investigating the intimia media thickness and plaques on carotid artery and to analyze the risk factors of CAD. METHODS: Using B mode ultrasonography, the intimia media thickness of carotid artery was measured and the risk factors of CAD were analyzed in CAD group of 69 patients, who were divided into 3 subgroups ( 20 in 1 vessel group, 23 in 2 vessel group and 26 in 3 vessel group) and 21 subjects with normal coronary arteries as control. RESULTS: The intimia media thickness of CAD group was significantly higher than that of the control group and no significant difference was observed among the 1, 2 and 3 vessel groups. Atherosclerotic plaques were found mostly in the carotid bifurcation and common carotid artery segments. The discovery rate of atherosclerotic plaques was higher in 2 and 3 vessel groups. The content of TC and LDL C, and the incidence of hypertension and diabetes mellitus were higher in the CAD group. CONCLUSION: CAD is positively associated with the severity of atherosclerosis in carotid artery. Risk factors of CAD can be predicted by carotid ultrasound imagining.
Keywords:carotid arteries  atherosclerosis/ultrasonography  coronary  disease/ultrasonography  risk factors
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