| 腹腔化疗在进展期胃癌根治术后的治疗作用新评价 |
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| 引用本文： | 徐大志,耿其荣,林桐榆,詹友庆,李威,陈映波,孙晓卫,关远祥,李元方.腹腔化疗在进展期胃癌根治术后的治疗作用新评价[J].第四军医大学学报,2009,30(5):443-446. |
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| 作者姓名： | 徐大志 耿其荣 林桐榆 詹友庆 李威 陈映波 孙晓卫 关远祥 李元方 |
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| 作者单位： | 徐大志,詹友庆,李威,陈映波,孙晓卫,关远祥,李元方,XU Da-Zhi,ZHAN You-Qing,LI Wei,CHEN Ying-Bo,SUN Xiao-Wei,GUAN Yuan-Xiang,LI Yuan-Fang(华南肿瘤学国家重点实验室,广东,广州,510060;中山大学肿瘤防治中心腹科,广东,广州,510060);耿其荣,林桐榆,GENG Qi-Rong,LIN Tong-Yu(华南肿瘤学国家重点实验室,广东,广州,510060;中山大学肿瘤防治中心内科,广东,广州,510060)
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| 摘 要： | 目的：探讨腹腔化疗在进展期胃癌治疗中的作用．方法：利用Meta分析的方法，对国内外已发表的12篇随机对照研究进行定量综合，应用Cochrane协作网提供的RevMan4．2软件进行统计分析，以OR值作为结局变量．结果：入选的12篇文献，共有患者1249例．合计OR=0．53，95％置信区间（0．42～0．67），说明了腹腔化疗优势明显．亚组分析表明，对于来自亚洲、进行腹腔温热化疗或含活性碳粒的腹腔内化疗的患者，效果尤为突出．敏感性分析与失效安全数计算证实本结论较为可靠．但仅有试验4个质量较高，使得研究结论的证据力度有所降低．结论：进展期胃癌根治术后行腹腔化疗可能对患者有益．
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| 关 键 词： | 胃肿瘤 腹腔化疗 Meta分析 |
Role of intraperitoneal chemotherapy after radical resection of local advanced gastric cancer |
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| XU Da-Zhi,GENG Qi-Rong,LIN Tong-Yu,ZHAN You-Qing,LI Wei,CHEN Ying-Bo,SUN Xiao-Wei,GUAN Yuan-Xiang,LI Yuan-Fang, State Key Laboratory of Oncology in South China,Guangzhou ,China.Role of intraperitoneal chemotherapy after radical resection of local advanced gastric cancer[J].Journal of the Fourth Military Medical University,2009,30(5):443-446. |
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| Authors: | XU Da-Zhi GENG Qi-Rong LIN Tong-Yu ZHAN You-Qing LI Wei CHEN Ying-Bo SUN Xiao-Wei GUAN Yuan-Xiang LI Yuan-Fang State Key Laboratory of Oncology in South China Guangzhou China |
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| Institution: | XU Da-Zhi1,2,GENG Qi-Rong1,3,LIN Tong-Yu1,ZHAN You-Qing1,LI Wei1,CHEN Ying-Bo1,SUN Xiao-Wei1,GUAN Yuan-Xiang1,LI Yuan-Fang1,2 1State Key Laboratory of Oncology in South China,Guangzhou 510060,China,2Department of Abdominal Surgery,Cancer Center,Sun Yat-sen University,3Department of Medical Oncology |
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| Abstract: | AIM: To assess the role of intraperitoneal chemotherapy(IPT) in patients with gastric carcinoma after radial resection.METHODS: We reviewed 12 randomized controlled trials about IPT in local advanced gastric cancer and made a meta-analysis.The statistical analysis was performed by RevMan4.2 software provided by the Cochrane Collaboration.The result was expressed with odds ratio(OR) for the categorical variable.RESULTS: Twelve trials of 1249 cases were included.The pooled OR was 0.53,with a 95% confidence in... |
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| Keywords: | stomach nsoplasms intraperitoneal chemotherapy Meta-analysis |
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