| 结肠癌中p73基因改变的意义 |
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| 引用本文： | 李陕区,刘变英.结肠癌中p73基因改变的意义[J].第四军医大学学报,2000,21(3):314-316. |
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| 作者姓名： | 李陕区 刘变英 |
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| 作者单位： | [1]第四军医大学全军基因诊断技术研究所 [2]太原市第264医院内镜中心 |
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| 摘 要： | 研究Ｐ７３基因在结肠癌中的改变及其意义，方法采用ＰＣＲ－ＳＳＣＰ方法检测４０例结肠癌及其癌帝非癌组织中Ｐ７３基因突变，采用定量ＲＴ－ＣＲ方法检测Ｐ７３基因的表达。结果①ＰＣＲ－ＳＳＣＰ检测出７例存在Ｐ７３等位基因缺失，未见突变；②定量ＲＴ－ＰＣＲ检测出３３例结肠癌呈高表达，７例呈中等表达，非癌列呈低水平表达。
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| 关 键 词： | 结肠癌 p73基因 定量RT－PCR |
| 修稿时间： | 1999-12-14 |
Alteration of p73 gene in colon cancer and paracancerous tissues and its significance |
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| LI Shan Qu ,CUI Da Xiang ,LIU Bian Ying ,YAN Xiao Jun ,SUN An Le ,GUO Yan Hai ,DUAN Jie ,SU Cheng ZHi Institute of Genetic Diagnosis Technology of Chinese PLA,Fourth Military Medical University,Xi'an ,China.Alteration of p73 gene in colon cancer and paracancerous tissues and its significance[J].Journal of the Fourth Military Medical University,2000,21(3):314-316. |
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| Authors: | LI Shan Qu CUI Da Xiang LIU Bian Ying YAN Xiao Jun SUN An Le GUO Yan Hai DUAN Jie SU Cheng ZHi Institute of Genetic Diagnosis Technology of Chinese PLA Fourth Military Medical University Xi'an China |
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| Institution: | LI Shan Qu 1,CUI Da Xiang 1,LIU Bian Ying 2,YAN Xiao Jun 1,SUN An Le 2,GUO Yan Hai 1,DUAN Jie 1,SU Cheng ZHi 1 1Institute of Genetic Diagnosis Technology of Chinese PLA,Fourth Military Medical University,Xi'an 710033,China |
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| Abstract: | |
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| Keywords: | colon cancer p73 gene quantitative RT-PCR |
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