| 大鼠次声刺激后脑组织谷氨酸的变化 |
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| 引用本文： | 傅国友,陈景藻,贾克勇.大鼠次声刺激后脑组织谷氨酸的变化[J].第四军医大学学报,1999,20(4):288-290. |
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| 作者姓名： | 傅国友 陈景藻 贾克勇 |
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| 作者单位： | 第四军医大学西京医院理疗科,陕西,西安,710033 |
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| 摘 要： | 目的：观察大鼠暴露于次声环境后脑组织中谷氨酸（Ｇｌｕ）的变化。方法 把大鼠置于不同的次声环境中暴露２ｈ，观察８Ｈｚ／９０ｄＢ暴露组，８Ｈｚ／１２０ｄＢ暴露组，１６Ｈｚ／９０ｄＢ暴露组，１６Ｈｚ／１２０ｄＢ暴露组及正常对照组大鼠脑组织海马区Ｇｌｕ的变化规律。结果；与对照组相比，８Ｈｚ／１２０ｄＢ暴露组和１６Ｈｚ／１２０ｄＢ暴露组脑组织海马区谷氨酸含量明显增加；１６Ｈｚ／１２０ｄＢ暴露组脑组织海马区谷
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| 关 键 词： | 次声 谷氨酸 海马 大鼠 |
Changes of glutamate in brain of rats exposed to infrasound |
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| FU Guo-You,CHEN Jing-Zao,JIA Ke-Yong.Changes of glutamate in brain of rats exposed to infrasound[J].Journal of the Fourth Military Medical University,1999,20(4):288-290. |
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| Authors: | FU Guo-You CHEN Jing-Zao JIA Ke-Yong |
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| Abstract: | AIM: To investigate the changes of glutamate (Glu) in brain of rats exposed to infrasound. METHODS: Rat model was established by putting the rats in the environment of infrasound for two hours. The rats were divided into five groups: normal control, 8 Hz/90 dB, 8 Hz/120 dB, 16 Hz/90 dB and 16 Hz/120 dB. RESULTS: Compared with the control group, the content of Glu in cerebral hippocampus was higher in 8 Hz/120 dB group and 16 Hz/120 group(P<0.01);The elevation of Glu content in 16 Hz/120 dB group was more significant than that in 8 Hz/120 dB group (P<0.01). HZCONCLUSION: The infrasound effect on the brain is related to the frequency and sound grade, and the latter is the key factor. The exciting toxicity of Glu may play a more important role in the injury of brain by infrasound. |
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| Keywords: | infrasound glutamate hippocampus rat |
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