| 电磁脉冲对大鼠视交叉上核及松果体中Fos蛋白表达的影响 |
| |
| 引用本文： | 曲润江,郭鹞,王淑芳,郑振兴.电磁脉冲对大鼠视交叉上核及松果体中Fos蛋白表达的影响[J].第四军医大学学报,2000,21(8):936-939. |
| |
| 作者姓名： | 曲润江 郭鹞 王淑芳 郑振兴 |
| |
| 作者单位： | 1. 第四军医大学预防医学系放射医学教研室,陕西,西安,710033
2. 第四军医大学唐都医院病理科 |
| |
| 基金项目： | 军队重点研究项目，98Z084， |
| |
| 摘 要： | 目的：观察电磁脉冲（ＥＭＰ）照射后大鼠视交叉上核（ＳＣＮ）与松果体（ＰＧ）中Ｆｏｓ蛋白表达情况，探讨ＥＭＰ对大鼠尽夜节律的影响及其机制。方法采用ＳＡＢＣ免疫组织化学染色法对ＥＭＰ照射后大鼠ＳＣＮ与ＰＧ中Ｆｏｓ阳性神经元的变化进行检测。结果光照早期照射组，大鼠ＳＣＮ与ＰＧ组织中Ｆｏｓ阳性细胞率及染色灰度值对照组相比无明显差异（Ｐ。〉０．。０５）；黑暗早期照射组ＳＣＮ的Ｆｏｓ阳性细胞率比对照组增高，染
|
| 关 键 词： | 电磁脉冲 视交叉上核 松果体 Fos蛋白 免疫组化 |
Effects of electromagnetic pulse on Fos protein in hypothalamic suprachiasmatic nucleus and pineal glands of rats |
| |
| QU Run-Jiang,GUO Yao,WANG Shu-Fang,ZHENG Zhen-Xing.Effects of electromagnetic pulse on Fos protein in hypothalamic suprachiasmatic nucleus and pineal glands of rats[J].Journal of the Fourth Military Medical University,2000,21(8):936-939. |
| |
| Authors: | QU Run-Jiang GUO Yao WANG Shu-Fang ZHENG Zhen-Xing |
| |
| Abstract: | AIM To observe the involvement of Fos protein in the changes of circadian rhythm regulation of rats caused byexposure to electromagnetic pulse (EMP) and investigate the distribution of Fos protein expression in hypothalamic suprachiasmatic nucleus (SCN) and pineal gland(GP) of rats following exposure to EMP. METHODS SABC immunohistochemical staining was employed to determine the distribution of Fos protein. RESULTS\ The positive rate of cells and the gray grade values in the middle dark phase group were significantly different from the control groups respectively, whereas those in the middle light phase groups were not. CONCLUSION\ These data confirm that EMP exposure does have some effects on the changes of Fos protein in SCN and PG of rats. These data can also prove the influence of EMP on circadian rhythm and may help explain the mechanism of the influence. |
| |
| Keywords: | electromagnetics suprachiasmatic nucleus pineal gland Fos protein immunohistochemistry image analysis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
