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546例肝炎后肝硬化患者的流行病学和临床特点
引用本文:白宪光,张丽环,何文革,连建奇.546例肝炎后肝硬化患者的流行病学和临床特点[J].第四军医大学学报,2000,21(7):820-823.
作者姓名:白宪光  张丽环  何文革  连建奇
作者单位:1. 第四军医大学唐都医院感染科,陕西,西安,710038
2. 甘肃武警总队医院
摘    要:目的 探讨肝炎后肝硬化的流行病学和临床特点。方法 对546例肝炎后肝硬化的住院病例进行回顾性调查分析。结果 肝炎肝硬化年龄主要分布在31 ̄60岁,男女比例为4.31:1;单纯乙肝后肝硬化430例,占78.8%,乙肝重叠其他肝炎病毒84例,占15.4%;肝炎反复发作较不发作发展为肝硬化的时间明显缩短;胃镜检查发现84.1%的肝炎肝硬化患有食管胃静3工张,B超声显示7.9%的肝硬化患脾体积正

关 键 词:病毒性肝炎  肝硬化  流行病学  临床特点

Epidemiologic and clinical features of 546 patients with posthepatitic cirrhosis
BAI Xian-Guang,ZHANG Li-Huan,HE Wen-Ge,LIAN Jian-QI.Epidemiologic and clinical features of 546 patients with posthepatitic cirrhosis[J].Journal of the Fourth Military Medical University,2000,21(7):820-823.
Authors:BAI Xian-Guang  ZHANG Li-Huan  HE Wen-Ge  LIAN Jian-QI
Abstract:AIM To investigate the epidemiologic and clinical features of the patients with posthepatitic cirrhosis. METHODS By retrospective analysis, 546 in-patients with posthepatitic cirrhosis were studied. RESULTS The age of cases was predominantly 31~60, with a sex ratio of 4.31(M):1(F). 430 cases were determined as hepatitis B, accounting for 78.8 percent of the patients. 84 cases suffered from hepatitis B superinfecting other hepatitic viruses, holding 15.4 percent of all patients. The period for the patients with recurrent hepatitis to evolve to liver cirrhosis was significantly shorter than that for the patients with no relapse. Gastroesophageal varices were discovered in 84.1 percent of the patients by gastroscopy. Normal size of spleens was confirmed in 7.9 percent of all cases by type B ultrasonography. The incidence of portal hypertensive gastropathy increased with size of esophageal varices. There is 30.8% percent of portal hypertensive gastropathy in the patients without gastroesophageal varices. Of 114 cases with upper gacstrointestinal bleeding, that of 31.0 percent of patients resulted from gastroesophageal varices, while 61.9 and 7.1 percent of cases were due to portal hypertensive gastropathy and peptic ulcer respectively. CONCLUSION The posthepatitis B cirrhosis is a main type of cirrhosis in China. Simultaneous examination of ultrasonography and gastroscopy contributes to enhancing diagnosis of liver cirrhosis. Development of portal hypertensive gastropathy is influenced by portal hypertension and severity of liver disease. Portal hypertensive gastropathy and gastroesophageal varices are important factors of upper gastrointestinal bleeding.
Keywords:viral hepatitis  hepatocirrhosis  epidemiology
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