实验动物骨性关节炎内侧副韧带力学特性

目的比较正常和骨性关节炎动物模型膝关节内侧副韧带的拉伸力学性能指标，确定骨性关节炎对内侧副韧带拉伸力学性质有无影响。方法实验用大鼠由长春高新医学动物实验中心提供，均为6月龄雄性大鼠复制骨性关节炎模型。在日本岛津电子万能试验机上对正常和病态组各10个试样进行拉伸实验。拉伸实验的速度为5mm／min。以多项式用最小二乘法处理实验数据。结果正常对照组最大载荷为（26．12±4．00）N，最大应力为（40．93±6．71）MPa，最大位移为（3．08±0．77）mm，最大应变为（9．51±2．36）％；模型组最大载荷为（12．05±2．07）N，最大应力为（21．28±4．17）MPa，最大位移为（2．32±0．56）mm，最大应变为（7．04±1．79）％。结论正常对照组各项拉伸性能指标显著大于模型组（P〈0．05），骨性关节炎对膝关节内侧副韧带力学性质具有一定影响。

The Mechanical Properties of Medial Collateral Ligament in Animal Model of Osteoarthritis

Objective To compare the mechanical properties of animal knee lateral collateral ligament tensile between the normal and atherosclerotic animal model of osteoarthritis,and to identify if there are effects of osteoarthritis on the animal knee lateral collateral ligament tensile mechanical properties.Methods The experimental rats were provided by the Changchun High Medical Center for animal experiments.The 6-month-old male rats were the copying model of osteoarthritis.The tensile experiments at electron Shima...