| 胃癌患者术前中性粒细胞淋巴细胞比率与淋巴结转移相关性临床研究 |
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| 引用本文： | 李晨,杜晓辉,徐迎新,陈凛,夏绍友,张勇.胃癌患者术前中性粒细胞淋巴细胞比率与淋巴结转移相关性临床研究[J].医学研究杂志,2015,44(1):93-97. |
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| 作者姓名： | 李晨 杜晓辉 徐迎新 陈凛 夏绍友 张勇 |
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| 作者单位： | 中国人民解放军总医院普外科,北京,100853 |
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| 摘 要： | 目的探讨胃癌患者术前中性粒细胞淋巴细胞比率(NLR)与淋巴结转移的关系,指导胃癌术中淋巴结的清扫。方法回顾2006年1月~2008年12月于笔者所在科室行胃癌根治术患者244例,男性184例(75.4%),女性60例(24.6%),平均年龄58.3(29~85)岁。收集患者术前中性粒细胞计数、淋巴细胞计数、血小板计数。以NLR=4为临界点将患者分为高NLR组及低NLR组。收集患者术中切除淋巴结数,计算淋巴结转移率、转移度。按清扫总数是否>15枚分为≥15枚组及<15枚组。按肿瘤大小、Borrmann分型及术中淋巴结清扫进行分层分析。结果淋巴结转移率(度),NLR≥4组高于NLR<4组。淋巴结转移≥N1,NLR≥4的患者比例明显较高,淋巴结分期增高(P<0.05)。NLR均值高,肿瘤直径≥4cm,BorrmannⅢ、Ⅳ型患者增加。术中淋巴结清扫总数,术前NLR均值偏高者大于偏低者,差异有统计学意义(P<0.05)。结论术前NLR对患者术前淋巴结分期有提示作用,可做为术前淋巴结分期的补充并对术中淋巴结清扫有指导意义,可做为术前确定淋巴结清扫范围和清扫数量的参考指标之一。
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| 关 键 词： | 胃癌 中性粒细胞淋巴细胞比率 淋巴结 转移 预后 |
| 收稿时间： | 2014/4/21 0:00:00 |
| 修稿时间： | 2014/6/30 0:00:00 |
Correlation between Preoperative Neutrophil Lymphocyte Ratio in Gastric Cancer Patients with Lymphnode Metastasis |
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| Li Chen,Du Xiaohui,Xu Yingxin.Correlation between Preoperative Neutrophil Lymphocyte Ratio in Gastric Cancer Patients with Lymphnode Metastasis[J].Journal of Medical Research,2015,44(1):93-97. |
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| Authors: | Li Chen Du Xiaohui Xu Yingxin |
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| Institution: | Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China;Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China;Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China;Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China;Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China;Department of Surgery, Clinical Division, The Chinese People's Liberation Army General Hospital, Beijing 100853, China |
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| Abstract: | |
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| Keywords: | Gastric cancer Neutrophil lymphocyte ratio Lymphnodes Metastasis Prognosis |
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